Roxadustat Impurity 163 CAS 62202-62-4
| CAS No. | 62202-62-4 |
| Molecular Formula | C12H16N2O5S |
| Molecular Weight | 300.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Roxadustat Impurity 163 (CAS 62202-62-4) is a certified pharmaceutical impurity reference standard with the molecular formula C12H16N2O5S and a molecular weight of 300.33 g/mol.
Structurally, Roxadustat Impurity 163 (C12H16N2O5S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 300.33 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O5S |
| Molecular Weight | 300.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Roxadustat Standards
- Roxadustat Impurity 131 (CAS CATO-C4X-2213131)
- Roxadustat Impurity 64 (CAS 1509958-11-5)
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- Roxadustat Impurity 99 (CAS CATO-C4X-221399)
- Roxadustat Impurity N15 (CAS 1455091-10-7)
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Recommended Standards
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- Lemborexant Impurity 70 (CAS CATO-C4X-304270)
- Elagolix Impurity 24 (CAS CATO-C4X-206824)
- Isavuconazole Impurity 34 (CAS CATO-C4X-123635)
- Emtricitabine Impurity 57 (CAS 1773498-61-5)
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