Posaconazole Impurity 174 CAS 2169241-14-7
| CAS No. | 2169241-14-7 |
| Molecular Formula | C12H15FO2 |
| Molecular Weight | 210.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Posaconazole Impurity 174 (CAS 2169241-14-7, C12H15FO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C12H15FO2, Posaconazole Impurity 174 contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 210.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Posaconazole Impurity 174 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15FO2 |
| Molecular Weight | 210.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
Related Posaconazole Standards
- Posaconazole Impurity 175 (CAS 169265-99-0)
- Posaconazole Impurity 164 (CAS CATO-C4X-1208164)
- Posaconazole Impurity 112 (CAS 110931-77-6)
- Posaconazole Impurity 66 (CAS 1428118-25-5)
- Posaconazole Impurity 119 (CAS 2243786-03-8)
- Posaconazole impurity 219 (CAS CATO-C4X-1208219)
- Posaconazole Impurity 262(R/S Mixture) (CAS CATO-C4X-1208262)
- Posaconazole Impurity 86 (CAS 170985-84-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com