3-(4-Chlorophenyl)-1H-pyrrole-2,5-dione CAS 21724-87-8
| CAS No. | 21724-87-8 |
| Molecular Formula | C10H6ClNO2 |
| Molecular Weight | 207.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-Chlorophenyl)-1H-pyrrole-2,5-dione.
CATO supplies 3-(4-Chlorophenyl)-1H-pyrrole-2,5-dione (CAS 21724-87-8), a certified reference material (molecular formula C10H6ClNO2, MW 207.61 g/mol) for analytical method development and quality control.
Structurally, 3-(4-Chlorophenyl)-1H-pyrrole-2,5-dione (C10H6ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 207.61 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-Chlorophenyl)-1H-pyrrole-2,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6ClNO2 |
| Molecular Weight | 207.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- 1-(2-Chlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 1203-24-3)
- 1-(3-Chlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 1204-35-9)
- 3-(4-Chlorophenyl)isoxazole-5-carbaldehyde (CAS 121769-18-4)
- 1-(4-Chlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 1631-29-4)
- (3-Chlorophenyl)(oxazol-2-yl)methanone (CAS 898759-75-6)
- (4-Chlorophenyl)(oxazol-2-yl)methanone (CAS 898759-77-8)
- 2-(2-Chlorophenyl)oxazole-4-carbaldehyde (CAS 885274-43-1)
- 2-(3-Chlorophenyl)oxazole-4-carbaldehyde (CAS 885273-15-4)
Recommended Standards
- 3-(3-Chloro-phenyl)-isoxazole-5-carbaldehyde (CAS 869496-60-6)
- 3-(Oxazol-2-yl)benzoyl chloride (CAS 473538-14-6)
- 3-(2-Chlorophenyl)isoxazole-5-carbaldehyde (CAS 337355-80-3)
- 3-Chloro-1-nitronaphthalene (CAS 56961-39-8)
- trans-2-fluorocyclohexanamine;hydrochloride (CAS 75198-16-2)
- 2-Amino-2-(2-bromo-5-methoxyphenyl)acetic acid (CAS 1031705-87-9)
- 2-(6-Nitropyridin-3-yl)acetic acid (CAS 1504882-22-7)
- 2-(Phenoxymethyl)-1H-benzo[d]imidazole (CAS 6637-29-2)
- Dichloro[(4S,5S)-(+)-4,5-bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane][(S)-(-)-2-(t-butyl)methanamine)-1H-benzimidazole]ruthenium(II) (CAS 1443051-98-6)
- Methyl 3-bromo-5-(trifluoromethyl)thiophene-2-carboxylate (CAS 1823362-55-5)
- N-(3-(5,7-Dimethylbenzo[d]oxazol-2-yl)-2-methylphenyl)-2-methoxybenzamide (CAS 590395-79-2)
- Diphenoxylate EP Impurity B (CAS 4370-12-1)
- 3-[2-(3-Methylbutanamido)phenoxy]thiophene-2-carboxylic acid (CAS 900019-05-8)
- Des-Ser34-Gly33Tirzepatide (CAS CATO-CPTD788941)
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