2-(Chloromethyl)-3-(4-chlorophenyl)-2-methyl-2,3-dihydroquinazolin-4(1H)-one CAS 217461-92-2

Purity 97%+In StockPharmaceutical Standards
CAS No.217461-92-2
Molecular FormulaC16H14Cl2N2O
Molecular Weight321.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Chloromethyl)-3-(4-chlorophenyl)-2-methyl-2,3-dihydroquinazolin-4(1H)-one CAS 217461-92-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Chloromethyl)-3-(4-chlorophenyl)-2-methyl-2,3-dihydroquinazolin-4(1H)-one.

CATO supplies 2-(Chloromethyl)-3-(4-chlorophenyl)-2-methyl-2,3-dihydroquinazolin-4(1H)-one (CAS 217461-92-2), a certified reference material (molecular formula C16H14Cl2N2O, MW 321.20 g/mol) for analytical method development and quality control.

Based on its molecular formula C16H14Cl2N2O, 2-(Chloromethyl)-3-(4-chlorophenyl)-2-methyl-2,3-dihydroquinazolin-4(1H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 321.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Chloromethyl)-3-(4-chlorophenyl)-2-methyl-2,3-dihydroquinazolin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H14Cl2N2O
Molecular Weight321.20 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2019
Halogen ContentCl-containing
Nitrogen Atoms2

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