Indobufen Impurity 16 CAS 21762-22-1
| CAS No. | 21762-22-1 |
| Molecular Formula | C10H11NO4 |
| Molecular Weight | 209.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Indobufen Impurity 16 (CAS 21762-22-1, C10H11NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Indobufen Impurity 16 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 209.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11NO4 |
| Molecular Weight | 209.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
Related Indobufen Standards
- Indobufen Impurity 15 (CAS 160723-33-1)
- Indobufen Impurity 19 (CAS 7463-53-8)
- Indobufen Impurity N9 (CAS 858006-96-9)
- Indobufen Impurity 73 (CAS CATO-C4X-179273)
- Indobufen Impurity 85 (CAS CATO-C4X-179285)
- Indobufen Impurity 45 (CAS CATO-C4X-179245)
- Indobufen Impurity 46 (CAS CATO-C4X-179246)
- Indobufen Impurity 52 (CAS 57960-84-6)
Recommended Standards
- N-Nitroso- Prazosin EP Impurity D (CAS CATO-C4X-17362)
- Nintedanib Impurity 165 (CAS 1351810-29-1)
- Metoclopramide Impurity 40 (CAS 4093-28-1)
- Bosutinib Impurity 7 (CAS 142072-71-7)
- Topiramate Impurity 29 (CAS 53209-14-6)
- Tolvaptan Impurity 7 (CAS 1346599-75-4)
- Tofacitinib Impurity 230 (CAS CATO-C4X-1079230)
- 3-(2,6-Dibromophenyl)propanoic acid (CAS 957211-37-9)
- 3-Bromo-6-chloro-2-methylbenzoic acid (CAS 1345025-12-8)
- 2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazole (CAS 141177-76-6)
- 637344-08-2 2-Amino(2-~13~C)ethan-1-ol DTXSID40514696 (CAS 637344-08-2)
- 3-(4-Fluorophenyl)-2-(methylthio)pyrimidin-4(3H)-one (CAS 89069-21-6)
- N-(2,4-Dichlorophenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142200-26-7)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com