4-Bromo-2-chloro-6-fluorobenzonitrile CAS 218797-72-9
| CAS No. | 218797-72-9 |
| Molecular Formula | C7H2BrClFN |
| Molecular Weight | 234.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 234.45 g/mol gives 4-Bromo-2-chloro-6-fluorobenzonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Bromo-2-chloro-6-fluorobenzonitrile (CAS 218797-72-9), molecular formula C7H2BrClFN and molecular weight 234.45 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Bromo-2-chloro-6-fluorobenzonitrile (C7H2BrClFN) is characterized by a nitrile group, fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Bromo-2-chloro-6-fluorobenzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H2BrClFN |
| Molecular Weight | 234.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 5-Bromo-3-chloro-2-fluorobenzonitrile (CAS 1000577-76-3)
- 4-Bromo-2-chloro-5-fluorobenzonitrile (CAS 1126779-33-6)
- 3-Bromo-5-chloro-2-fluorobenzonitrile (CAS 1160574-15-1)
- 4-Bromo-3-chloro-2-fluorobenzonitrile (CAS 1160574-68-4)
- 4-Bromo-5-chloro-2-fluorobenzonitrile (CAS 1349716-15-9)
- 3-Bromo-4-chloro-5-fluorobenzonitrile (CAS 1357944-86-5)
- 3-Bromo-2-chloro-6-fluorobenzonitrile (CAS 1421620-33-8)
- 4-Bromo-2-chloro-3-fluorobenzonitrile (CAS 1427439-32-4)
Recommended Standards
- 3-Bromo-6-chloro-2-fluorobenzonitrile (CAS 943830-79-3)
- 1,2-Dihexyldisulfane (CAS 10496-15-8)
- 3-Bromo-4-chloro-2-fluorobenzonitrile (CAS 2092624-38-7)
- (4-Chlorophenyl)(3-fluorophenyl)(hydroxy)borane (CAS 872495-47-1)
- 2-{[(tert-butoxy)carbonyl]amino}-4-methylpent-4-enoic acid (CAS 156047-41-5)
- 2-(3-Methoxypiperidin-1-yl)acetic acid (CAS 1353987-64-0)
- Ethyl 3-(4-(2-(5-ethylpyridin-2-yl)ethoxy)phenyl)-2-thioxopropanoate (CAS 1246816-33-0)
- 1-(4-Bromobenzenesulfonyl)piperidine-4-carboxylic acid (CAS 203519-01-1)
- 2-(But-3-en-1-yl)cyclopentan-1-ol (CAS 140902-66-5)
- 4-Chloro-N-2-propen-1-yl-3-(trifluoromethyl)benzenesulfonamide (CAS 730986-30-8)
- (R)-1-(1-Methylpiperidin-2-yl)propan-2-one (CAS 40199-45-9)
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