Benzydamine EP Impurity A HCl CAS 2196185-65-4
| CAS No. | 2196185-65-4 |
| Molecular Formula | C19H24N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Benzydamine EP Impurity A HCl.
CATO supplies Benzydamine EP Impurity A HCl (CAS 2196185-65-4), a pharmacopoeial impurity reference standard (molecular formula C19H24N2O2HCl, MW 348.87 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H24N2O2HCl, Benzydamine EP Impurity A HCl contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 348.87 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H24N2O2 HCl |
| Molecular Weight | 348.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Benzydamine Standards
- Benzydamine Impurity 9 (CAS 100922-96-1)
- Benzydamine-d6 Hydrochloride (CAS 1246817-20-8)
- Benzydamine-d6 N-Oxide (CAS 1246820-03-0)
- Benzydamine Impurity D Hydrochloride (CAS 1281-00-1)
- Benzydamine Hydrochloride (CAS 132-69-4)
- Benzydamine Hydrochloride EP Impurity D (CAS 1337966-15-0)
- Benzydamine EP Impurity B HCl (CAS 2196183-71-6)
- Benzydamine EP Impurity C (CAS 2215-63-6)
Recommended Standards
- Esomeprazole Impurity 144 (CAS CATO-C4X-1112144)
- Testosterone Impurity 13 (CAS 17305-49-6)
- Clopidogrel Impurity 36 HCl (CAS 1346605-15-9 (free base))
- Cefotiam Impurity 42 (CAS CATO-C4X-120442)
- 7-(Pyridin-4-yl)-9-(trifluoromethyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione (CAS 625376-68-3)
- Ethyl 3-amino-3-phenyl-2,3,3a,4-tetrahydrobenzo[b]thiophene-2-carboxylate (CAS 84538-85-2)
- 4-[Acetyl(methyl)amino]benzoic acid (CAS 26961-99-9)
- 2,3-Dichloro-N-(3-chlorophenyl)-4-(ethylsulfonyl)benzamide (CAS 477867-75-7)
- Baclofen Impurity 38 (CAS CATO-C4X-101238)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
Why CATO?
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