Baclofen Impurity 38 CAS CATO-C4X-101238
| CAS No. | CATO-C4X-101238 |
| Molecular Formula | C11H12ClNO3 |
| Molecular Weight | 241.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Baclofen Impurity 38 (CAS CATO-C4X-101238, C11H12ClNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Baclofen Impurity 38 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 241.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C11H12ClNO3 |
| Molecular Weight | 241.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Baclofen Standards
- Baclofen EP Impurity B (CAS 1141-23-7)
- Baclofen Impurity 37 (CAS CATO-C4X-101237)
- Baclofen Impurity 41 (CAS 159156-84-0)
- Baclofen impurity 12 (CAS 232597-00-1)
- Baclofen impurity 18 (CAS CATO-C4X-101218)
- Baclofen Impurity 40 (CAS CATO-C4X-101240)
- Baclofen EP Impurity C (CAS 35271-74-0)
- Baclofen impurity 7 (CAS 103857-58-5)
Recommended Standards
- Palbociclib Impurity 197 (CAS 1314997-73-3)
- N-acetyl-2-chloro- L-Phenylalanine (CAS 103522-34-5)
- Lornoxicam Impurity N1 (CAS 1017791-22-8)
- 2-Chloro-N-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-acetamide 757220-20-5 9281AE C11H12ClNO3 (CAS 757220-20-5)
- Abiraterone Impurity 8 (CAS CATO-C4X-10708)
- Iguratimod Impurity 83 HCl (CAS CATO-C4X-182683)
- Tadalafil EP Impurity B (CAS 629652-72-8)
- 4'-Butyl-[1,1'-biphenyl]-4-thiol (CAS 107336-77-6)
- 5-[(5-Cyano-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)methyl]-4,5-dihydro-1,2-oxazole-3-carbohydrazide (CAS 339279-29-7)
- methyl 5-amino-1,3-thiazole-2-carboxylate (CAS 1363381-19-4)
- Pramipexole Impurity 48 (CAS CATO-C4X-110748)
- Pitavastatin Impurity 84 (CAS CATO-C4X-103784)
- 4-Bromo-2-fluoro-N-isopropylbenzenesulfonamide (CAS 1055995-88-4)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
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