4-(2-(2-Methoxyphenyl)-3-(4-nitrophenyl)acrylamido)benzene-1-sulfonyl fluoride CAS 21970-48-9
| CAS No. | 21970-48-9 |
| Molecular Formula | C22H17FN2O6S |
| Molecular Weight | 456.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(2-(2-Methoxyphenyl)-3-(4-nitrophenyl)acrylamido)benzene-1-sulfonyl fluoride.
CATO supplies 4-(2-(2-Methoxyphenyl)-3-(4-nitrophenyl)acrylamido)benzene-1-sulfonyl fluoride (CAS 21970-48-9), a certified reference material (molecular formula C22H17FN2O6S, MW 456.44 g/mol) for analytical method development and quality control.
The molecular framework of 4-(2-(2-Methoxyphenyl)-3-(4-nitrophenyl)acrylamido)benzene-1-sulfonyl fluoride (C22H17FN2O6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(2-(2-Methoxyphenyl)-3-(4-nitrophenyl)acrylamido)benzene-1-sulfonyl fluoride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H17FN2O6S |
| Molecular Weight | 456.44 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methoxyphenyl Standards
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Recommended Standards
- 2-((1R,4r)-4-(4-(5-((3,4-difluorophenyl)amino)-1,3,4-oxadiazole-2-carboxamido)phenyl)cyclohexyl)acetic acid (CAS 892489-52-0)
- N-(5-((2-((2-Fluorophenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-2-(trifluoromethyl)benzamide (CAS 391869-31-1)
- (3-Amino-6-(p-tolyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(benzo[d][1,3]dioxol-5-yl)methanone (CAS 488122-26-5)
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- (S)-5-Chloro-2,3-dihydro-1H-inden-1-amine hydrochloride (CAS 1376687-76-1)
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- 2-Hydroxy-1,4-Naphthoquinone (CAS 83-72-7)
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- 2-Bromo-1-butene (CAS 23074-36-4)
- 2,6-Dichlorophenylmethylsulfoxide (CAS 122199-98-8)
- (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine 2-Amino-4-(methylphosphino)butyrylalanylalanine 35597-43-4 Antibiotic SF 1293 Bialaphos CHEBI:3088 L-phosphinothricyl-L-alanyl-L-alanine N-{(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl}-L-alanyl-L-alanine PTT Phosphinothricylalanylalanine bilanafos gamma-(Hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-L-alanine phosphinothricin tripeptide (CAS 35597-43-4)
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