Bosutinib Impurity 10 CAS 219786-51-3
| CAS No. | 219786-51-3 |
| Molecular Formula | C10H12BrNO4 |
| Molecular Weight | 290.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Bosutinib Impurity 10 (CAS 219786-51-3), a pharmacopoeial impurity reference standard (molecular formula C10H12BrNO4, MW 290.11 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C10H12BrNO4, Bosutinib Impurity 10 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 290.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12BrNO4 |
| Molecular Weight | 290.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bosutinib Standards
- Bosutinib 4-Hydroxy 7-Chloropropoxy Impurity (CAS 214470-66-3)
- Bosutinib 4-Chloro 7-Chloropropoxy Impurity (CAS 214470-68-5)
- Bosutinib Impurity 13 (CAS CATO-C4X-184713)
- Bosutinib Impurity 29 (CAS 846023-24-3)
- Bosutinib Impurity 9 (CAS 92878-95-0)
- Bosutinib Impurity N5 (CAS 263149-10-6)
- Bosutinib Impurity 28 (CAS 65182-98-1)
- Bosutinib Impurity N3 (CAS 17722-32-6)
Recommended Standards
- Methyl 4-Bromo-6-cyano-2-naphthoate (CAS 371220-18-7)
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- 2-[N-(2-Methoxyethyl)methanesulfonamido]acetic acid (CAS 956019-97-9)
- 1-(6-(4-Ethylpiperazin-1-yl)-5-methylpyridin-3-yl)ethan-1-ol (CAS 1355219-09-8)
- Methanesulfonamide, 1,1,1-trifluoro-N-[(11bR)-8,9,10,11,12,13,14,15-octahydro-4-oxido-2,6-bis[4-(trifluoromethyl)phenyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl]- (CAS 2757287-56-0)
- 6-Aminoquinolin-2-ol (CAS 79207-68-4)
- Liraglutide(5-31)TFA Salt (CAS CATO-C4X-19924)
Why CATO?
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