Ticagrelor Impurity 7 CAS 220347-05-7
| CAS No. | 220347-05-7 |
| Molecular Formula | C21H24F2N6O3S |
| Molecular Weight | 478.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Ticagrelor Impurity 7 (CAS 220347-05-7, C21H24F2N6O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C21H24F2N6O3S, Ticagrelor Impurity 7 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 478.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H24F2N6O3S |
| Molecular Weight | 478.52 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor impurity 166 (CAS CATO-C4X-1093166)
- Ticagrelor Impurity 79 (CAS CATO-C4X-109379)
- Ticagrelor metabolite-M8 D7 (CAS 220347-05-7 (unlabelled))
- Ticagrelor Impurity 38 (CAS 1644461-81-3)
- Ticagrelor Impurity 187 (CAS CATO-C4X-1093187)
- Ticagrelor Impurity 37 (CAS CATO-C4X-109337)
- Ticagrelor Impurity 116 (CAS 1863036-47-8)
- Ticagrelor Impurity 48 (CAS CATO-C4X-109348)
Recommended Standards
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- Montelukast Impurity 40 (CAS CATO-C4X-103140)
- Minoxidil Impurity 44 (CAS 1637646-87-7)
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