Ticagrelor Impurity 37 CAS CATO-C4X-109337
| CAS No. | CATO-C4X-109337 |
| Molecular Formula | C21H24F2N6O4S |
| Molecular Weight | 494.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Ticagrelor Impurity 37 (CAS CATO-C4X-109337) is a certified pharmaceutical impurity reference standard with the molecular formula C21H24F2N6O4S and a molecular weight of 494.51 g/mol.
Structurally, Ticagrelor Impurity 37 (C21H24F2N6O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 494.51 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H24F2N6O4S |
| Molecular Weight | 494.51 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor metabolite-M8 D7 (CAS 220347-05-7 (unlabelled))
- Ticagrelor Impurity 80 (CAS CATO-C4X-109380)
- Ticagrelor Impurity 14 (CAS 1643378-47-5)
- Ticagrelor Impurity 54 (CAS CATO-C4X-109354)
- Ticagrelor Impurity 177 (CAS CATO-C4X-1093177)
- Ticagrelor Impurity 7 (CAS 220347-05-7)
- Ticagrelor impurity 166 (CAS CATO-C4X-1093166)
- Ticagrelor Impurity 79 (CAS CATO-C4X-109379)
Recommended Standards
- Methyl 4-(((4-methyl-5-(2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazol-4-yl)-4H-1,2,4-triazol-3-yl)thio)methyl)benzoate (CAS 956606-98-7)
- 3-((1R,3R)-3-(5-(4-Fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-5-methyl-1,2,4-oxadiazole (CAS 1104599-69-0)
- Methyl 3-[2-({2-[3-(trifluoromethyl)benzamido]phenyl}sulfanyl)acetamido]thiophene-2-carboxylate (CAS 477887-59-5)
- O-Methyl-N-(9H-purin-6-yl)hydroxylamine (CAS 17124-24-2)
- Tapentadol EP Impurity C (CAS 731764-76-4)
- Azathioprine Impurity 11 (CAS 4897-21-6)
- Mometasone Furoate Impurity 25 (CAS CATO-C4X-170425)
- 2-(Dimethylamino)thiazole-4-carbaldehyde (CAS 521956-44-5)
- (5,5-Difluoro-1-methylpiperidin-3-yl)methanol (CAS 2757097-14-4)
- N-butyroÂylmorpholine (CAS 5327-51-5)
- 2,2,2-Trifluoroethyl (3-methyl-1-(pyridin-2-yl)-1H-pyrazol-5-yl)carbamate (CAS 2126177-80-6)
- Teriflunomide Impurity 2 (CAS 69066-42-8)
- (1R,2S,5R)-tert-Butyl 2-amino-8-azabicyclo[3.2.1]octane-8-carboxylate (CAS 1932591-63-3)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
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