4,6-Difluorobenzimidazole CAS 2208-24-4
| CAS No. | 2208-24-4 |
| Molecular Formula | C7H4F2N2 |
| Molecular Weight | 154.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,6-Difluorobenzimidazole is closely related to a nitrile group, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4,6-Difluorobenzimidazole (CAS 2208-24-4), a certified reference material (molecular formula C7H4F2N2, MW 154.12 g/mol) for analytical method development and quality control.
4,6-Difluorobenzimidazole (C7H4F2N2) contains a nitrile group, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,6-Difluorobenzimidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4F2N2 |
| Molecular Weight | 154.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorobenzimidazole Standards
Recommended Standards
- 4,6-Difluoro-1H-pyrrolo[3,2-c]pyridine (CAS 2756329-79-8)
- 4,6-Dihydroxynicotinamide (CAS 5466-41-1)
- 4,5-Dihydro-1H-furo[2,3-c]pyrazole-3-carboxylic acid (CAS 595610-49-4)
- 4-Amino-2,6-difluorobenzonitrile (CAS 207297-92-5)
- Ethyl4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triphenylmethyl)-1h-pyrazole-3-carboxylate (CAS 2170134-91-3)
- 2-Hydrazinylpyrimidine-5-carbohydrazide (CAS 287714-38-9)
- Abz-Gln-Val-Val-Ala-Gly-Ala-EDDnp (M-2100.0001) (CAS 152390-52-8)
- (S)-N-(Pyrrolidin-3-yl)methanesulfonamide hydrochloride (CAS 1312686-83-1)
- Canagliflozin Impurity 77 (CAS CATO-C4X-112377)
- N'-(6-chloropyridin-2-yl)cyclopropanecarbohydrazide (CAS 478064-08-3)
- Ethyl 6-(phenylcarbamoyl)-4-(trifluoromethyl)pyridine-2-carboxylate (CAS 1210182-96-9)
- 6-Chloro-2-(3-ethoxyphenyl)quinoline-4-carboxylic acid (CAS 897560-16-6)
- 2-Thioxo-5-(4-(trifluoromethyl)benzyl)thiazolidin-4-one (CAS 905267-14-3)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
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