Canagliflozin Impurity 77 CAS CATO-C4X-112377
| CAS No. | CATO-C4X-112377 |
| Molecular Formula | C18H14FIS |
| Molecular Weight | 408.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Canagliflozin Impurity 77 (CAS CATO-C4X-112377) is a certified pharmaceutical impurity reference standard with the molecular formula C18H14FIS and a molecular weight of 408.27 g/mol.
Structurally, Canagliflozin Impurity 77 (C18H14FIS) contains sulfur-containing functionality, fluorine/iodine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 408.27 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Canagliflozin Impurity 77 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14FIS |
| Molecular Weight | 408.27 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/I-containing |
| Sulfur Atoms | 1 |
Related Canagliflozin Standards
- Canagliflozin Impurity 20 (CAS CATO-C4X-112320)
- Canagliflozin Impurity 27 (CAS 898566-17-1)
- Canagliflozin Impurity 51 (CAS 2444540-10-5)
- Canagliflozin Impurity 52 (CAS CATO-C4X-112352)
- Canagliflozin Impurity 53 (CAS CATO-C4X-112353)
- Canagliflozin Impurity 54 (CAS CATO-C4X-112354)
- Canagliflozin Impurity 55 (CAS CATO-C4X-112355)
- Canagliflozin Impurity 76 (CAS 2952941-15-8)
Recommended Standards
- Canagliflozin Impurity 80 (CAS CATO-C4X-112380)
- Canagliflozin Impurity 81 (CAS CATO-C4X-112381)
- Canagliflozin Impurity 82 (CAS CATO-C4X-112382)
- Canagliflozin Impurity 83 (CAS CATO-C4X-112383)
- Cabazitaxel Impurity 35 (CAS CATO-C4X-111535)
- Ticagrelor Impurity 123 (CAS 2512210-19-2)
- Cefoperazone Impurity N10 (CAS 59032-27-8)
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