6-Phenyl-4-(trifluoromethyl)-2-pyridone CAS 22122-89-0
| CAS No. | 22122-89-0 |
| Molecular Formula | C12H12F3NO |
| Molecular Weight | 243.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Phenyl-4-(trifluoromethyl)-2-pyridone.
CATO supplies 6-Phenyl-4-(trifluoromethyl)-2-pyridone (CAS 22122-89-0), a certified reference material (molecular formula C12H12F3NO, MW 243.22 g/mol) for analytical method development and quality control.
The molecular framework of 6-Phenyl-4-(trifluoromethyl)-2-pyridone (C12H12F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Phenyl-4-(trifluoromethyl)-2-pyridone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12F3NO |
| Molecular Weight | 243.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Phenyl Standards
- 5-(Trifluoromethyl)-2H-spiro[benzofuran-3,3'-pyrrolidine] (CAS 1047657-74-8)
- 5-(2-(Trifluoromethyl)phenoxy)pentanenitrile (CAS 1303743-39-6)
- 5-(3-(Trifluoromethyl)phenoxy)pentanenitrile (CAS 1307520-98-4)
- 3-(4-(Trifluoromethyl)benzyl)pyrrolidin-2-one (CAS 1350989-17-1)
- 1-(4-(Trifluoromethyl)benzyl)pyrrolidin-2-one (CAS 1353087-69-0)
- 1-(3-(Trifluoromethyl)phenyl)piperidin-4-one (CAS 147378-74-3)
- 4-Methyl-4-(3-(trifluoromethyl)phenyl)pyrrolidin-2-one (CAS 1488856-28-5)
- 4-Methyl-4-(4-(trifluoromethyl)phenyl)pyrrolidin-2-one (CAS 1494528-00-5)
Recommended Standards
- 6-Methyl-2-(5-nitrofuran-2-yl)imidazo[1,2-a]pyridine (CAS 61982-57-8)
- 7-(Benzyloxy)-[1,2,5]oxadiazolo[3,4-d]pyrimidin-5-amine (CAS 90180-92-0)
- 6-Ethoxy-5-nitroquinoline-4-carbonitrile (CAS 54524-96-8)
- 7,7-Dimethyl-2-(trifluoromethyl)-7,8-dihydroquinolin-5(6H)-one (CAS 205582-86-1)
- 3-Acetyl-5-chlorobenzenesulfonyl chloride (CAS 1152589-88-2)
- 6-(Bromomethyl)benzo[d]oxazole (CAS 181040-42-6)
- (3S)-3-methylpyrrolidine-3-carboxylic acid (CAS 1427203-57-3)
- 5-(4-Methoxyphenyl)-3-perfluorooctyl-1H-pyrazole (CAS 1029636-52-9)
- 9-(2-Methylbut-3-en-2-yl)-9H-purin-6-amine (CAS 7369-97-3)
- (S)-1-(4-(Methylsulfonyl)phenyl)ethanamine (CAS 1037798-64-3)
- 3-(2-Hydroxybenzylidene)dihydrofuran-2(3H)-one (CAS 4736-29-2)
- Cytarabine Impurity 7 (CAS CATO-C4X-20057)
- 4-Methylimidazole (CAS 822-36-6)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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