Pazopanib Impurity 17 CAS 221681-92-1
| CAS No. | 221681-92-1 |
| Molecular Formula | C9H11N3 |
| Molecular Weight | 161.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Pazopanib Impurity 17 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Pazopanib Impurity 17 (CAS 221681-92-1) is a certified pharmaceutical impurity reference standard with the molecular formula C9H11N3 and a molecular weight of 161.20 g/mol.
Based on its molecular formula C9H11N3, Pazopanib Impurity 17 contains a nitrogen-containing heterocyclic scaffold, a nitrile group; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 161.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Pazopanib Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11N3 |
| Molecular Weight | 161.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Nitrogen Atoms | 3 |
Related Pazopanib Standards
- Pazopanib Impurity 57 (CAS CATO-C4X-172557)
- Pazopanib Impurity 9 (CAS 444731-72-0)
- Pazopanib Impurity 29 (CAS 20191-74-6)
- Pazopanib Impurity 59 (CAS CATO-C4X-172559)
- Pazopanib Impurity 20 (CAS 3934-20-1)
- Pazopanib Impurity 58 (CAS CATO-C4X-172558)
- Pazopanib Impurity 60 (CAS CATO-C4X-172560)
- Pazopanib Impurity 30 (CAS 1313372-75-6)
Recommended Standards
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- Atorvastatin Impurity 27 (CAS 693793-82-7)
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- 2-Ethoxy-4-methoxy-1-nitrobenzene (CAS 151929-97-4)
- 1-(2-Methylquinolin-4-yl)piperidin-4-ol (CAS 927801-80-7)
- (Asn5)-Delta-Sleep Inducing Peptide (H-2555.0005) (CAS 80064-67-1)
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