Atorvastatin Impurity 27 CAS 693793-82-7
| CAS No. | 693793-82-7 |
| Molecular Formula | C26H23F2NO3 |
| Molecular Weight | 435.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Atorvastatin Impurity 27 (CAS 693793-82-7) is a certified pharmaceutical impurity reference standard with the molecular formula C26H23F2NO3 and a molecular weight of 435.46 g/mol.
Atorvastatin Impurity 27 (C26H23F2NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Atorvastatin Impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H23F2NO3 |
| Molecular Weight | 435.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Atorvastatin Standards
- Atorvastatin EP Impurity D (CAS 148146-51-4)
- Atorvastatin Impurity 99 (CAS CATO-C4X-113299)
- Atorvastatin Calcium EP Impurity D (CAS 873950-19-7)
- Atorvastatin Impurity 86 (CAS 1046118-44-8)
- Atorvastatin Impurity 103 (CAS 1797905-42-0)
- Atorvastatin Oxirane Impurity (CAS 1246818-88-1)
- Atorvastatin Impurity 82 (CAS 125971-96-2)
- Atorvastatin Impurity 154 (CAS 1331869-19-2)
Recommended Standards
- 6-(Benzo[d][1,3]dioxol-5-yl)-2-((2-(piperidin-1-yl)ethyl)thio)-4-(trifluoromethyl)nicotinonitrile (CAS 625376-93-4)
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- 2-Amino-4-(trifluoromethyl)thiazole-5-carbonitrile (CAS 151729-42-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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