4-Iodo-N,N-dimethylbenzenesulfonamide CAS 22184-85-6
| CAS No. | 22184-85-6 |
| Molecular Formula | C8H10INO2S |
| Molecular Weight | 311.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Iodo-N,N-dimethylbenzenesulfonamide (CAS 22184-85-6), a certified reference material (molecular formula C8H10INO2S, MW 311.14 g/mol) for analytical method development and quality control.
4-Iodo-N,N-dimethylbenzenesulfonamide (C8H10INO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Iodo-N,N-dimethylbenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10INO2S |
| Molecular Weight | 311.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 4-[3,5-dichloro-2-(difluoromethoxy)phenyl]-1,3-thiazol-2-amine (CAS 790232-39-2)
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- N-(4-iodophenyl)ethanesulfonamide (CAS 61738-45-2)
- N1-(2-Bromo-4-(trifluoromethyl)phenyl)-N2,N2-dimethylethane-1,2-diamine (CAS 1547425-86-4)
- Ethyl 3-methyl-4-oxo-4,7-dihydroisothiazolo[5,4-b]pyridine-5-carboxylate (CAS 1134188-34-3)
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