Nintedanib Impurity 12 CAS 2218446-42-3
| CAS No. | 2218446-42-3 |
| Molecular Formula | C17H13NO4 |
| Molecular Weight | 295.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 295.29 g/mol gives Nintedanib Impurity 12 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Nintedanib Impurity 12 (CAS 2218446-42-3) is a certified pharmaceutical impurity reference standard with the molecular formula C17H13NO4 and a molecular weight of 295.29 g/mol.
Nintedanib Impurity 12 (C17H13NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nintedanib Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H13NO4 |
| Molecular Weight | 295.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
Related Nintedanib Standards
- Nintedanib Impurity 3 (CAS 2093243-16-2)
- Nintedanib Impurity 5 (CAS 2036139-30-5)
- Nintedanib Impurity 163 (CAS CATO-C4X-1814163)
- Nintedanib Impurity 166 (CAS 126434-07-9)
- Nintedanib Impurity 126 (CAS CATO-C4X-1814126)
- Nintedanib Impurity 130 (CAS CATO-C4X-1814130)
- Nintedanib Impurity 131 (CAS CATO-C4X-1814131)
- Nintedanib Impurity 159 (CAS CATO-C4X-1814159)
Recommended Standards
- Omeprazole Impurity 44 (CAS CATO-C4X-125544)
- Oxcarbazepine Impurity 22 (CAS 2642430-30-4)
- Olaparib Impurity 148 (CAS CATO-C4X-1135148)
- Penciclovir Impurity 2 (CAS 97845-80-2)
- Pregabalin Impurity 130 (CAS CATO-C4X-1312130)
- Dextromethorphan Impurity 37 (CAS 2382909-24-0)
- Lasmiditan Impurity 62 (CAS CATO-C4X-247862)
- 2-(8-Hydroxyquinolin-5-yl)acetonitrile (CAS 57434-83-0)
- (5,5-Dimethylpyrrolidin-3-yl)methanol (CAS 1784056-43-4)
- 1-[2-(dimethylamino)ethyl]-1H-pyrazole-5-carboxylic acid dihydrochloride (CAS 1909325-49-0)
- Tert-butyl d-histidinate (CAS 777051-62-4)
- (R)-1-(3-bromophenyl)-2-methylpropan-1-amine (CAS 1212173-09-5)
- 4,4'-Bis(oxiran-2-ylmethoxy)-1,1'-biphenyl (CAS 2461-46-3)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com