(5-Cyclopropyl-2-(trifluoromethyl)pyridin-4-yl)boronic acid CAS 2225175-30-2
| CAS No. | 2225175-30-2 |
| Molecular Formula | C9H9BF3NO2 |
| Molecular Weight | 230.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 230.98 g/mol gives (5-Cyclopropyl-2-(trifluoromethyl)pyridin-4-yl)boronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(5-Cyclopropyl-2-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 2225175-30-2), molecular formula C9H9BF3NO2 and molecular weight 230.98 g/mol, is a CATO reference standard with documented purity and traceability.
(5-Cyclopropyl-2-(trifluoromethyl)pyridin-4-yl)boronic acid (C9H9BF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9BF3NO2 |
| Molecular Weight | 230.98 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cyclopropyl Standards
- (2-Cyclopropyl-6-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 1446486-08-3)
- (2-Cyclopropyl-5-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2225176-76-9)
- (5-Cyclopropyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2225154-87-8)
- (6-Cyclopropyl-5-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2225173-40-8)
- (2-Cyclopropyl-5-(pyrrolidin-1-yl)phenyl)boronic acid (CAS 2225172-09-6)
- (3-Cyclopropyl-5-(pyrrolidin-1-yl)phenyl)boronic acid (CAS 2225169-97-9)
- 1-Cyclopropyl-1-(3,4-dichlorophenyl)ethanol (CAS 1247496-38-3)
- 1-Cyclopropyl-1-(3,4-dichlorophenyl)ethan-1-ol (CAS 1379310-89-0)
Recommended Standards
- 3-(Bromomethyl)-5-(trifluoromethyl)-1,2,4-oxadiazole (CAS 1609396-23-7)
- 3-Iodopyrazine-2-carbonitrile (CAS 1062608-54-1)
- [3-Cyano-4-(trifluoromethoxy)phenyl]boronic acid (CAS 2268800-99-1)
- 5-Iodopyrimidine-2-carbonitrile (CAS 1083329-46-7)
- 2-Methoxy-4-{[(prop-2-en-1-yl)amino]methyl}phenol hydrochloride (CAS 1240567-34-3)
- Tert-butyl2-(4-(benzyloxy)-1-ethoxy-1,3-dioxobutan-2-ylidene)hydrazine-1-carboxylate (CAS 1674398-09-4)
- 5-(2-(3-Chlorophenyl)benzo[d]oxazol-5-yl)-1,3,4-oxadiazol-2-amine (CAS 1706449-46-8)
- 1-[(3-Methylphenyl)methyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one (CAS 303988-03-6)
- (4-Methoxy-2-nitrophenyl)glycine (CAS 55687-28-0)
- 3-Bromo-4-chloro-5-hydroxybenzoic acid (CAS 1823372-67-3)
- 3,5-Dichloro-4-(difluoromethoxy)phenol (CAS 1807060-48-5)
- 1,5-Dihydrodipyrrolo[1,2-a:2',1'-d][1,3,5]triazine (CAS 221546-22-1)
- Ethyl 4-isobutylpiperidine-4-carboxylate (CAS 1227243-23-3)
- Cholecystokinin Octapeptide (1-4) (desulfated) (CAS 80790-40-5)
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