(2-Chloro-3-methyl-5-(trifluoromethyl)phenyl)boronic acid CAS 2225174-50-3
| CAS No. | 2225174-50-3 |
| Molecular Formula | C8H7BClF3O2 |
| Molecular Weight | 238.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2-Chloro-3-methyl-5-(trifluoromethyl)phenyl)boronic acid.
(2-Chloro-3-methyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225174-50-3) is a high-purity analytical reference standard with the molecular formula C8H7BClF3O2 and a molecular weight of 238.40 g/mol.
(2-Chloro-3-methyl-5-(trifluoromethyl)phenyl)boronic acid (C8H7BClF3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2-Chloro-3-methyl-5-(trifluoromethyl)phenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7BClF3O2 |
| Molecular Weight | 238.40 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-Chloro-2-methyl-4-(trifluoromethyl)phenylboronic acid (CAS 1072946-33-8)
- (2-Chloro-4-methyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225169-10-6)
- (4-Chloro-2-methyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225181-01-9)
- 2-Chloro-N-(2,3-dichlorophenyl)acetamide (CAS 33560-47-3)
- 2-Chloro-N-(2,4-dichlorophenyl)acetamide (CAS 6974-56-7)
- 2-Chloro-N-(2,5-dichlorophenyl)acetamide (CAS 22303-26-0)
- 2-Chloro-N-(3,4-dichlorophenyl)acetamide (CAS 20149-84-2)
- 4-Chloro-3,5-bis(trifluoromethyl)-1H-pyrazole (CAS 287966-51-2)
Recommended Standards
- (2-((tert-Butyldimethylsilyl)oxy)phenyl)methanol (CAS 96013-79-5)
- Dimethoxy(methyl)(2-methyl-2-phenylpropyl)silane (CAS 157223-33-1)
- (3-((tert-Butyldimethylsilyl)oxy)phenyl)methanol (CAS 96013-77-3)
- 4-((tert-Butyldimethylsilyl)oxy)benzene-1,2-diamine (CAS 1416374-31-6)
- 6-Chloro-7-(chloromethyl)-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 87779-37-1)
- 2-Chloro-4-methoxybenzenethiol (CAS 89793-44-2)
- (6-chloro-4-phenylquinazolin-2-yl)methanol (CAS 30739-34-5)
- Diltiazem Impurity 11 (CAS 81353-09-5)
- 1142199-33-4 (4E)-3-(Chloromethyl)-4-(thiophen-3-ylmethylidene)-1,2-oxazol-5(4H)-one MFCD12027802 (CAS 1142199-33-4)
- (2-(6-(Azepan-1-yl)pyridin-3-yl)pyrrolidin-1-yl)(phenyl)methanone (CAS 1352499-72-9)
- Methyl 3-(4-isopropylphenyl)-3-[(2-thienylcarbonyl)amino]propanoate (CAS 477858-90-5)
- 2-((5-(4-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N,N-diphenylacetamide (CAS 332161-53-2)
- 1-(3-Chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-67-2)
- Anti-TF Antigen Peptide P30-1 trifluoroacetate salt (CAS 573664-50-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com