1-(3-Chloro-4,5-dimethoxyphenyl)-2,2,2-trifluoroethan-1-amine CAS 2229486-93-3
| CAS No. | 2229486-93-3 |
| Molecular Formula | C10H11ClF3NO2 |
| Molecular Weight | 269.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 269.65 g/mol gives 1-(3-Chloro-4,5-dimethoxyphenyl)-2,2,2-trifluoroethan-1-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(3-Chloro-4,5-dimethoxyphenyl)-2,2,2-trifluoroethan-1-amine (CAS 2229486-93-3) is a high-purity analytical reference standard with the molecular formula C10H11ClF3NO2 and a molecular weight of 269.65 g/mol.
The molecular framework of 1-(3-Chloro-4,5-dimethoxyphenyl)-2,2,2-trifluoroethan-1-amine (C10H11ClF3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(3-Chloro-4,5-dimethoxyphenyl)-2,2,2-trifluoroethan-1-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11ClF3NO2 |
| Molecular Weight | 269.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 1-(4-Chlorophenyl)-2-(pyrazin-2-yl)ethanone (CAS 83227-49-0)
- 3-[(4-fluorophenyl)methyl]-5-(pyrrolidin-2-yl)-1,2,4-oxadiazole hydrochloride (CAS 1311315-96-4)
- 2-(3,4-Dichlorophenyl)-2-oxoacetaldehyde (CAS 38923-36-3)
- (3-Bromo-6-(tetrahydro-2H-pyran-4-yl)pyridin-2-yl)methanamine (CAS 2585650-45-7)
- 2’-Cyano-2,2,2-trifluoroacetophenone Hydrate (CAS 1134303-97-1)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
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