Ethyl 2-chloro-3-cyano-6-methyl-5-nitroisonicotinate CAS 72701-63-4
| CAS No. | 72701-63-4 |
| Molecular Formula | C10H8ClN3O4 |
| Molecular Weight | 269.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Ethyl 2-chloro-3-cyano-6-methyl-5-nitroisonicotinate (CAS 72701-63-4), a certified reference material (molecular formula C10H8ClN3O4, MW 269.64 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Ethyl 2-chloro-3-cyano-6-methyl-5-nitroisonicotinate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 269.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Ethyl 2-chloro-3-cyano-6-methyl-5-nitroisonicotinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8ClN3O4 |
| Molecular Weight | 269.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 3-[(4-chloro-3-nitrophenyl)methyl]imidazolidine-2,4-dione (CAS 1097788-31-2)
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- 2-Chloro-N4-(furan-2-ylmethyl)-5-nitropyrimidine-4,6-diamine (CAS 326007-10-7)
- 3-(4-Chloro-3-nitrophenyl)-5-(methoxymethyl)-1,2,4-oxadiazole (CAS 879761-45-2)
- 5-Chloro-1,3-dimethyl-6-nitroquinazoline-2,4(1H,3H)-dione (CAS 78754-85-5)
- Ethyl 5-chloro-4-nitrobenzofuran-2-carboxylate (CAS 412336-55-1)
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Recommended Standards
- 5-(Chloromethyl)-3-((4-nitrophenoxy)methyl)-1,2,4-oxadiazole (CAS 306936-72-1)
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- 1-(3-Chloro-4,5-dimethoxyphenyl)-2,2,2-trifluoroethan-1-amine (CAS 2229486-93-3)
- (R)-2-(4,5-dichloro-2-fluorophenyl)pyrrolidine (CAS 1381928-46-6)
- 3-Chloro-2-iodo-4-(trifluoromethyl)pyridine (CAS 1227514-97-7)
- Methyl 2,2-difluorobutanoate (CAS 86966-96-3)
- 5-(4-Methoxyphenyl)-1,3-dithiane 1,1,3,3-tetraoxide (CAS 111012-67-0)
- 3-(3-Methylpiperidin-1-yl)butanoic acid (CAS 860225-58-7)
- 1-(2-Methoxy-5-methylphenyl)-3-methylbutan-1-one (CAS 854871-02-6)
- 2-(Difluoromethyl)-4-iodo-6-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1805552-22-0)
- (R)-3-amino-5-methylhexan-1-ol (CAS 925230-77-9)
- 1,2,3,4,6-pentagalloylglucose (CAS 14937-32-7)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
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