Xanomeline impurity 37 CAS 22346-73-2
| CAS No. | 22346-73-2 |
| Molecular Formula | C6H5NO2 |
| Molecular Weight | 123.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Xanomeline impurity 37 (C6H5NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Xanomeline impurity 37 (CAS 22346-73-2, C6H5NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Xanomeline impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5NO2 |
| Molecular Weight | 123.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
Related Xanomeline Standards
- Xanomeline impurity 28 (CAS CATO-C4X-330128)
- Xanomeline impurity 36 (CAS 98276-73-4)
- Xanomeline impurity 27 (CAS CATO-C4X-330127)
- Xanomeline Impurity 8 (CAS 131987-88-7)
- Xanomeline Impurity 17 (CAS 2644093-98-9)
- Xanomeline Impurity 7 (CAS CATO-C4X-33017)
- Xanomeline impurity 48 (CAS CATO-C4X-330148)
- Xanomeline Impurity 15 (CAS CATO-C4X-330115)
Recommended Standards
- Baricitinib Impurity 134 (CAS CATO-C4X-2260134)
- Chlorquinaldol impurity 2 (CAS 13168-78-0)
- Omeprazole Impurity 22 (CAS 2783-57-5)
- Pyrazinamide (CAS 98-96-4)
- Carbamazepine Impurity 33 (CAS 34124-14-6)
- Ramipril EP Impurity J (CAS 1246253-05-3)
- Cefotaxime Impurity 85 (CAS CATO-C4X-120185)
- 4-Aminoantipyrine N-Carbamic Acid Methyl Ester (CAS 10077-96-0)
- 3-(10-Bromodecyl)thiophene (CAS 125878-93-5)
- 4-Amino-3-(aminomethyl)-5-(difluoromethyl)picolinonitrile (CAS 1805269-76-4)
- Tetrazine-Amine (CAS 1092689-33-2)
- methyl N-(2-(tert-butoxy)acetyl)-O-(tert-butyldimethylsilyl)-L-serinate (CAS CATO-C4X-22644)
- 4-Amino-5-(difluoromethyl)-6-hydroxypyridine-2-sulfonamide (CAS 1805138-76-4)
- Cholecystokinin Octapeptide (1-3) (desulfated) H-Asp-Tyr-Met-OH (CAS 121880-94-2)
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