Baricitinib Impurity 134 CAS CATO-C4X-2260134
| CAS No. | CATO-C4X-2260134 |
| Molecular Formula | C5H5N3O |
| Molecular Weight | 123.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C5H5N3O, Baricitinib Impurity 134 contains an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 123.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Baricitinib Impurity 134 (CAS CATO-C4X-2260134, C5H5N3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5N3O |
| Molecular Weight | 123.11 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Nitrogen Atoms | 3 |
Related Baricitinib Standards
- Baricitinib Impurity 35 (CAS 25240-33-9)
- Baricitinib Impurity 34 (CAS 763120-58-7)
- Baricitinib Impurity 22 (CAS 2075-45-8)
- Baricitinib Impurity 31 (CAS 335654-06-3)
- Baricitinib Impurity N3 (CAS 136823-41-1)
- Baricitinib Impurity 33 (CAS 4843-98-5)
- Baricitinib Impurity 95 (CAS 1309430-77-0)
- Baricitinib Impurity 43 (CAS 1401222-91-0)
Recommended Standards
- Omeprazole Impurity 22 (CAS 2783-57-5)
- Xanomeline impurity 37 (CAS 22346-73-2)
- Bisacodyl Impurity 15 (CAS 7216-40-2)
- Chlorquinaldol impurity 2 (CAS 13168-78-0)
- Brivaracetam Impurity 152 (CAS CATO-C4X-2007152)
- [8-L-aspartic acid,12-glycine]Terlipressin (CAS CATO-C4X-219312)
- Glumetinib Impurity 4 (CAS CATO-C4X-32594)
- 1-((2-([1,1'-Biphenyl]-4-yl)-6-methylimidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid (CAS 728864-57-1)
- 3-(2-Nitrophenyl)propan-1-ol (CAS 20716-26-1)
- 2-(Bromomethyl)-7-chlorobenzo[b]thiophene (CAS 102246-40-2)
- Ethyl 4-(4-cyanophenyl)-2,4-dioxobutanoate (CAS 649557-55-1)
- 1-Fluoro-2,4-bis(bromomethyl)benzene (CAS 1379366-74-1)
- 7-methylbenzofuran-2-carboxylic acid (CAS 17349-64-3)
- Liraglutide Impurity 26 (CAS CATO-C4X-199226)
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