Melphalan EP Impurity G HCl salt CAS 2238824-44-5
| CAS No. | 2238824-44-5 |
| Molecular Formula | C26H35Cl3N4O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 610.40 g/mol gives Melphalan EP Impurity G HCl salt distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Melphalan EP Impurity G HCl salt (CAS 2238824-44-5), a pharmacopoeial impurity reference standard (molecular formula C26H35Cl3N4O4HCl, MW 610.40 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C26H35Cl3N4O4HCl, Melphalan EP Impurity G HCl salt contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 610.40 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Melphalan EP Impurity G HCl salt meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H35Cl3N4O4 2*HCl |
| Molecular Weight | 610.40 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Melphalan Standards
- Melphalan Isopropyl Ester (CAS 104874-57-9)
- Melphalan Impurity 14 (CAS 1088-80-8)
- Melphalan EP Impurity K (CAS 109-89-7)
- Melphalan-d (CAS 1217854-43-7)
- rac-Melphalan EP Impurity B (CAS 1259994-01-8)
- Melphalan EP Impurity B (CAS 1270153-04-2)
- D-Melphalan (CAS 13045-94-8)
- Melphalan Racemic Mixture (CAS 1465-26-5)
Recommended Standards
- Piribedil Impurity 18 (CAS CATO-C4X-281318)
- Ceritinib Impurity 29 (CAS CATO-C4X-104829)
- Lacidipine Impurity 6 (CAS CATO-C4X-16716)
- 6-(Methylamino)-2-phenylpyrimidin-4(3H)-one (CAS 31937-01-6)
- 1,5,7-Trimethyl-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4,6(5H)-dione (CAS 4318-52-9)
- Pyridoxine Impurity 60 (CAS 22464-27-3)
- [2,4-Difluoro-3-(propan-2-yloxy)phenyl]methanol (CAS 2230481-25-9)
- Eperisone impurity 11 (CAS CATO-C4X-227911)
- 3-[3-Methyl-4-(propan-2-yl)phenoxy]propane-1-sulfonyl chloride (CAS 1018549-08-0)
- D-Asp9-Tirzepatide (CAS CATO-CPTD788923)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com