rac-Melphalan EP Impurity B CAS 1259994-01-8
| CAS No. | 1259994-01-8 |
| Molecular Formula | C13H18N2O3 |
| Molecular Weight | 250.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
rac-Melphalan EP Impurity B (CAS 1259994-01-8) is a certified pharmaceutical impurity reference standard with the molecular formula C13H18N2O3 and a molecular weight of 250.29 g/mol.
rac-Melphalan EP Impurity B (C13H18N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18N2O3 |
| Molecular Weight | 250.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Related rac Standards
- Melphalan EP Impurity B (CAS 1270153-04-2)
- Melphalan EP Impurity C Hydrochloride (CAS 573704-41-3)
- Melphalan EP Impurity A (CAS 72143-20-5)
- Melphalan EP Impurity D (CAS 61733-01-5)
- Melphalan EP Impurity I (CAS 573704-40-2)
- Melphalan Impurity 14 (CAS 1088-80-8)
- Melphalan DL-isomer (CAS 531-76-0)
- Melphalan (CAS 148-82-3)
Recommended Standards
- Lornoxicam Impurity 43 (CAS CATO-C4X-201643)
- Tetracaine Impurity 39 (CAS 101265-45-6)
- Methoxamine Impurity 12 (CAS CATO-C4X-202212)
- Lacosamide Impurity 23 (CAS 1695551-74-6)
- Allisartan Isoproxil Impurity N2 (CAS 947331-10-4)
- Promestriene Impurity 9 (CAS 2575516-67-3)
- Roxatidine Impurity 14 (CAS CATO-C4X-121314)
- 1-Hydroxypyrazin-2(1H)-one (CAS 66313-29-9)
- tert-Butyl (2-ethyl-2-formylbutyl)carbamate (CAS 1820686-27-8)
- 1-(Pyridin-3-ylmethyl)piperidine-2-carboxylic acid (CAS 1025019-22-0)
- (11bR)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]-N,N-dimethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 1383348-53-5)
- 1-(5-Methyl-2-nitrophenoxy)-2-(2-nitrophenoxy)ethane (CAS 96315-08-1)
- 3-Isopropylpyridine-2-sulfonamide (CAS 2089377-22-8)
- Tirzepatide Impurity 1 (CAS 2460751-66-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com