Etravirine Impurity 7 CAS 2240161-92-4
| CAS No. | 2240161-92-4 |
| Molecular Formula | C25H24BrN7O2 |
| Molecular Weight | 534.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Etravirine Impurity 7 (CAS 2240161-92-4), a pharmacopoeial impurity reference standard (molecular formula C25H24BrN7O2, MW 534.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Etravirine Impurity 7 (C25H24BrN7O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H24BrN7O2 |
| Molecular Weight | 534.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 7 |
Related Etravirine Standards
Recommended Standards
- 1-{3-[(4-chlorobenzenesulfonyl)methyl]-4-nitrobenzoyl}-4-(4-chlorophenyl)piperazine (CAS 337921-09-2)
- Kaempferol-3-O-(6-Malonyl-Glucoside) (CAS 81149-02-2)
- para-iodoHoechst 33258 (CAS 158013-43-5)
- Luteoline-7-malonylglucoside (CAS 98767-38-5)
- Atrasentan Impurity 70 (CAS 1058349-20-4)
- Loperamide EP Impurity H (CAS 61299-42-1)
- Empagliflozin Impurity 47 (CAS 915095-99-7)
- 8-Chloro-6-fluoroquinoline (CAS 22319-88-6)
- 5-(Propan-2-yl)-4h,5h,6h,7h-[1,3]thiazolo[5,4-c]pyridine-2-carbaldehyde (CAS 1341653-34-6)
- 1-(4-Fluorophenyl)-2-(2-imino-2,3,4,5,6,7-hexahydro-1,3-benzothiazol-3-yl)ethan-1-one (CAS 745779-99-1)
- 4-(2-Chloro-6-fluorophenyl)-2-methyl-1-butene (CAS 951895-21-9)
- indole-7-methanol (CAS 1074-87-9)
- Glycinamide RibonucleotideDISCONTINUED (CAS 10074-18-7)
- TRAF6 Control Peptide trifluoroacetate salt (CAS 852690-80-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com