Dapoxetine Impurity 31 CAS 22422-21-5
| CAS No. | 22422-21-5 |
| Molecular Formula | C10H11ClO |
| Molecular Weight | 182.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Dapoxetine Impurity 31 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Dapoxetine Impurity 31 (CAS 22422-21-5, C10H11ClO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dapoxetine Impurity 31 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO |
| Molecular Weight | 182.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
Related Dapoxetine Standards
- Dapoxetine Impurity 53 (CAS 22422-27-1)
- Dapoxetine Impurity 25 (CAS 81402-52-0)
- Dapoxetine Impurity 27 (CAS 82769-75-3)
- Dapoxetine Impurity 78 (CAS 17733-68-5)
- Dapoxetine Impurity 36 (CAS 86-56-6)
- Dapoxetine Impurity 99 (CAS CATO-C4X-143999)
- Dapoxetine Impurity 37 (CAS 100306-34-1)
- Dapoxetine Impurity 74 (CAS 100306-33-0)
Recommended Standards
- 63667-85-6 1-(2-Chloroprop-2-en-1-yl)-2-methoxybenzene DTXSID40641178 (CAS 63667-85-6)
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- 3-(tert-Butyldimethylsilyloxy)glutaric Anhydride 52710-27-7 TRA-0206315 (CAS 52710-27-7)
- Glycerol Impurity 35 (CAS 18371-75-0)
- Dexrazoxane Impurity 6 (CAS CATO-C4X-20206)
- Brivaracetam impurity 102 (CAS CATO-C4X-2007102)
- Ceftazidime Impurity C68 (CAS 179258-52-7)
- 2-Bromo-4-(tert-butyl)-1-iodobenzene (CAS 860435-39-8)
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- 2-Nitro-4-(propylthio)aniline (CAS 54393-89-4)
- Thiamine Mononitrate (CAS 532-43-4)
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- Imidazo[1,2-a]pyrazine-3-carbonitrile (CAS 1208084-33-6)
- Tirzepatide(sodium salt) (CAS 2023788-19-2(free base))
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