Posaconazole Impurity 12(S,S,R,R) CAS 2243785-97-7
| CAS No. | 2243785-97-7 |
| Molecular Formula | C37H42F2N8O4 |
| Molecular Weight | 700.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 700.78 g/mol gives Posaconazole Impurity 12(S,S,R,R) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Posaconazole Impurity 12(S,S,R,R) (CAS 2243785-97-7) is a certified pharmaceutical impurity reference standard with the molecular formula C37H42F2N8O4 and a molecular weight of 700.78 g/mol.
Posaconazole Impurity 12(S,S,R,R) (C37H42F2N8O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Posaconazole Impurity 12(S,S,R,R) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C37H42F2N8O4 |
| Molecular Weight | 700.78 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Posaconazole Standards
- Posaconazole (CAS 171228-49-2)
- Posaconazole Impurity 13(R,R,R,R) (CAS 170985-61-2)
- Posaconazole Impurity 14(S,R,R,R) (CAS 213381-05-6)
- Posaconazole Impurity 15(S,S,S,S) (CAS 1246391-73-0)
- Posaconazole Impurity 157 (CAS CATO-C4X-1208157)
- Posaconazole Impurity 16(S,R,S,S) (CAS 213381-02-3)
- Posaconazole Impurity 17(R,R,R,S) (CAS 171228-51-6)
- Posaconazole Impurity 176 (CAS CATO-C4X-1208176)
Recommended Standards
- (D-Thr2)-Leu-Enkephalin-Thr (H-2775.0005) (CAS 85286-38-0)
- Sabutoclax (CAS 1228108-65-3)
- Suc-Ala-Phe-Pro-Phe-pNA (CAS 128802-73-3)
- Tezacaftor Impurity C28 (CAS 1294504-68-9)
- Vericiguat impurity 56 (CAS CATO-C4X-289656)
- Levocetirizine Impurity 52 (CAS CATO-C4X-108352)
- Indometacin Impurity 47 (CAS CATO-C4X-147047)
- 3'-SLea 3'-Sialyl Lewis A 92448-22-1 D-Glucose, O-(N-acetyl-a-neuraminosyl)-(2>3)-O-b-D-galactopyranosyl-(1>3)-O-[6-deoxy-a-L-galactopyranosyl-(1>4)]-2-(acetylamino)-2-deoxy- (9CI) D-glucose, O-5-(acetylamino)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranonosyl-(2->3)-O-beta-D-galactopyranosyl-(1->3)-O-[6-deoxy-alpha-L-galactopyranosyl-(1->4)]-2-(acetylamino)-2-deoxy- SLea Sialyl Lea tri Sialyl Lewis a Sialyl-Lewis a a-NeuNAc-(2>3)-b-D-Gal-(1>3)-(a-L-Fuc-[1>4])-D-GlcNAc (CAS 92448-22-1)
- 4-[3-(Trifluoromethyl)phenyl]oxane-4-carbonitrile (CAS 1035261-83-6)
- N-(3-Bromophenyl)-2-methoxyacetamide (CAS 430463-83-5)
- Quercetin-3-O-[α-L-rhamnose-(1→2)-β-D-glucopyranosyl]-5-O-β-D-glucopyranoside (CAS 80714-53-0)
- N-Methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-3-carboxamide (CAS 1708268-29-4)
- 1-(5-Chloro-2-methoxyphenyl)butan-1-ol (CAS 1215984-64-7)
- Fibrinogen-Binding Peptide (CAS 137235-80-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com