Posaconazole Impurity 13(R,R,R,R) CAS 170985-61-2
| CAS No. | 170985-61-2 |
| Molecular Formula | C37H42F2N8O4 |
| Molecular Weight | 700.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Posaconazole Impurity 13(R,R,R,R) (CAS 170985-61-2, C37H42F2N8O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Posaconazole Impurity 13(R,R,R,R) (C37H42F2N8O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 20.0, corresponding to approximately 20 ring(s) or double-bond equivalent(s). With a molecular weight of 700.78 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Posaconazole Impurity 13(R,R,R,R) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C37H42F2N8O4 |
| Molecular Weight | 700.78 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Posaconazole Standards
- Posaconazole (CAS 171228-49-2)
- Posaconazole Impurity 12(S,S,R,R) (CAS 2243785-97-7)
- Posaconazole Impurity 14(S,R,R,R) (CAS 213381-05-6)
- Posaconazole Impurity 15(S,S,S,S) (CAS 1246391-73-0)
- Posaconazole Impurity 157 (CAS CATO-C4X-1208157)
- Posaconazole Impurity 16(S,R,S,S) (CAS 213381-02-3)
- Posaconazole Impurity 17(R,R,R,S) (CAS 171228-51-6)
- Posaconazole Impurity 176 (CAS CATO-C4X-1208176)
Recommended Standards
- (D-Thr2)-Leu-Enkephalin-Thr (H-2775.0005) (CAS 85286-38-0)
- Sabutoclax (CAS 1228108-65-3)
- Suc-Ala-Phe-Pro-Phe-pNA (CAS 128802-73-3)
- Tezacaftor Impurity C28 (CAS 1294504-68-9)
- Irbesartan Impurity 21 (CAS CATO-C4X-166621)
- Lovastatin Impurity 18 (CAS CATO-C4X-168418)
- Acyclovir EP Impurity P (CAS 23169-33-7)
- 3,4-Dichloro-2-methylcinnamic acid (CAS 1807351-61-6)
- Ethyl 3-hydroxy-5-methylpicolinate (CAS 1806316-63-1)
- 4-(((2-Fluorophenyl)sulfonyl)methyl)pyridine (CAS 1325306-53-3)
- (3-(Hydroxymethyl)-4-(trifluoromethoxy)phenyl)boronic acid (CAS 1451393-59-1)
- 8-Bromo-7-methoxy-6-methyl-3,4-dihydronaphthalen-1(2H)-one (CAS 34403-74-2)
- 7-Bromo-8-fluoroquinazoline-2,4(1H,3H)-dione (CAS 2765352-55-2)
- Fibrinogen Related Peptide (CAS 80755-86-8)
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