1,3-Difluoro-2-(4-fluoro-5-iodo-2-methylphenoxy)-5-(trifluoromethyl)benzene CAS 2244086-98-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,3-Difluoro-2-(4-fluoro-5-iodo-2-methylphenoxy)-5-(trifluoromethyl)benzene.

1,3-Difluoro-2-(4-fluoro-5-iodo-2-methylphenoxy)-5-(trifluoromethyl)benzene (CAS 2244086-98-2), molecular formula C14H7F6IO and molecular weight 432.10 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a hydroxyl group, an ether linkage, fluorine/iodine substitution, a polycyclic aromatic system, 1,3-Difluoro-2-(4-fluoro-5-iodo-2-methylphenoxy)-5-(trifluoromethyl)benzene is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 432.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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