tert-Butyl (3-chloro-5-cyano-6-fluoro-9H-pyrido[2,3-b]indol-8-yl)(methyl)carbamate CAS 2245358-51-2
| CAS No. | 2245358-51-2 |
| Molecular Formula | C18H16ClFN4O2 |
| Molecular Weight | 374.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, tert-Butyl (3-chloro-5-cyano-6-fluoro-9H-pyrido[2,3-b]indol-8-yl)(methyl)carbamate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 374.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
tert-Butyl (3-chloro-5-cyano-6-fluoro-9H-pyrido[2,3-b]indol-8-yl)(methyl)carbamate (CAS 2245358-51-2) is a high-purity analytical reference standard with the molecular formula C18H16ClFN4O2 and a molecular weight of 374.80 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), tert-Butyl (3-chloro-5-cyano-6-fluoro-9H-pyrido[2,3-b]indol-8-yl)(methyl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16ClFN4O2 |
| Molecular Weight | 374.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Recommended Standards
- N-(4-chlorophenyl)-3-(2-nitrophenoxy)thiophene-2-carboxamide (CAS 252027-03-5)
- Afatinib Impurity 2 (CAS 314771-76-1)
- Methyl 1-(4-chlorophenyl)-6-oxo-4-(pyrimidin-2-ylthio)-1,6-dihydropyridazine-3-carboxylate (CAS 338756-23-3)
- Afatinib Impurity 21 (CAS 402855-03-2)
- 1-(3-Methoxyphenyl)butan-1-ol (CAS 1678-03-1)
- 3,5-Dimethyl-2-(1H-pyrrol-1-yl)pyrazine (CAS 239081-20-0)
- 5746-58-7 (12S)-12-Methyltetradecanoic acid DTXSID70581533 (CAS 5746-58-7)
- n-(3-(1h-Imidazol-1-yl)propyl)-2-methylbutan-1-amine (CAS 1038731-17-7)
- 6-Chloro-N-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-3-pyridazinamine (CAS 956781-87-6)
- 3,4-Bis(benzyloxy)aniline (CAS 18002-44-3)
- N-(tert-butyl)-2-nitrobenzamide (CAS 41225-78-9)
- 4-(5-Bromothiophen-2-yl)-2-(1H-pyrrol-1-yl)pyrimidine (CAS 860788-65-4)
- 1232804-19-1 4-(Chloromethyl)-2-(4-ethoxy-3-methoxyphenyl)-5-methyl-1,3-oxazole MFCD14703369 (CAS 1232804-19-1)
- Crustacean Cardioactive Peptide (CAS 107090-96-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com