2-(3-Chloro-2-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 2246545-93-5
| CAS No. | 2246545-93-5 |
| Molecular Formula | C13H15BClF3O2 |
| Molecular Weight | 306.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(3-Chloro-2-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246545-93-5), molecular formula C13H15BClF3O2 and molecular weight 306.52 g/mol, is a CATO reference standard with documented purity and traceability.
2-(3-Chloro-2-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (C13H15BClF3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-(3-Chloro-2-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H15BClF3O2 |
| Molecular Weight | 306.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-5-(trifluoromethyl)phenylboronic acid pinacol ester (CAS 1146214-95-0)
- 2-[4-Chloro-2-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1165935-85-2)
- 2-(3-Chloro-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1165935-97-6)
- 2-[2-chloro-4-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1165935-98-7)
- 2-Chloro-6-(trifluoromethyl)phenylboronic acid pinacol ester (CAS 1451391-09-5)
- 2-(4-Chloro-3-(difluoromethyl)-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1544563-33-8)
- 2-Chloro-3-(trifluoromethyl)phenylboronic acid pinacol ester (CAS 1689550-75-1)
- 2-(3-Chloro-6-(difluoromethyl)-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1802432-22-9)
Recommended Standards
- 2-(4-Chloro-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 445303-09-3)
- (2Z)-3-Methyl-4-(benzyloxy)-2-buten-1-ol tert-Butyldimethylsilyl Ether (CAS 1798394-47-4)
- 5-Chloro-2-(trifluoromethyl)phenylboronic acid pinacol ester (CAS 2121512-57-8)
- 5-Acetyl-2-(2,4,6-trichlorophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 1000572-21-3)
- 6-Bromo-N1,N1-dimethylbenzene-1,2-diamine (CAS 1369852-51-6)
- 7-Bromobicyclo[2.2.1]heptane (CAS 13237-88-2)
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- 3-(2-Chlorophenyl)-6-fluoro-2-methylquinazolin-4(3H)-one (CAS 49579-12-6)
- Dimethyl 5-(4-fluorophenyl)-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 2,2-dioxide (CAS 339113-46-1)
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- 3-chloro-4-methoxy-N-methylaniline (CAS 90234-41-6)
- 7-Bromobenzo[d]isothiazol-3-amine (CAS 1820034-73-8)
- Des-Ile12-Aib13-Tirzepatide (CAS CATO-CPTD788960)
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