Celecoxib Impurity 23 CAS 2247197-65-3
| CAS No. | 2247197-65-3 |
| Molecular Formula | C17H14F3N3O4S |
| Molecular Weight | 413.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Celecoxib Impurity 23 (CAS 2247197-65-3) is a certified pharmaceutical impurity reference standard with the molecular formula C17H14F3N3O4S and a molecular weight of 413.37 g/mol.
Structurally, Celecoxib Impurity 23 (C17H14F3N3O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 413.37 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Celecoxib Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H14F3N3O4S |
| Molecular Weight | 413.37 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Celecoxib Standards
- Celecoxib Impurity 51 (CAS CATO-C4X-104351)
- Celecoxib Impurity 65 (CAS CATO-C4X-104365)
- Celecoxib Impurity 3(Celecoxib Carboxylic Acid) (CAS 170571-01-4)
- Celecoxib Impurity 18 (CAS 2247197-67-5)
- Celecoxib Impurity 73 (CAS CATO-C4X-104373)
- Celecoxib Impurity 66 (CAS CATO-C4X-104366)
- Celecoxib Carboxylic Acid Methyl Ester (CAS 1189893-75-1)
- Celecoxib Impurity 41 (CAS 1803258-57-2)
Recommended Standards
- Methyl (S)-2-((tert-butoxycarbonyl)amino)-2-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)acetate (CAS 225517-17-9)
- 3-Bromo-5,5-diphenyl-5H-dibenzo[b,d]silole (CAS 1154752-07-4)
- Methyl (R)-2-((tert-butoxycarbonyl)amino)-2-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)acetate (CAS 313490-19-6)
- Methyl 3-(3-hydroxy-6-methyl-4-oxo-4H-pyran-2-yl)-3-(7-oxo-2,3,6,7-tetrahydro-[1,4]dioxino[2,3-g]quinolin-8-yl)propanoate (CAS 1574405-39-2)
- Ondansetron Impurity 14 (CAS 30354-18-8)
- Neostigmine Impurity N2 (CAS 64050-77-7)
- Calcipotriol Impurity 40 (CAS 2106840-41-7)
- 1-(6-Chloropyridin-3-yl)-N-methylmethanamine hydrochloride (CAS 1353973-69-9)
- N-(4-Fluorobenzyl)-5-methylfuro[3,2-b]pyridine-2-carboxamide (CAS 941969-19-3)
- 2-(9-(Tert-butoxycarbonyl)-1-oxa-9-azaspiro[5.5]Undecan-4-yl)acetic acid (CAS 2026649-89-6)
- 4-Bromo-2-chloro-1-(difluoromethoxy)benzene (CAS 1062614-42-9)
- tert-Butyl (5-bromo-1-cyano-2,3-dihydro-1H-inden-1-yl)carbamate (CAS 2007219-82-9)
- (1,1-dioxo-1H-benzo[d]isothiazol-3-ylsulfanyl)-acetonitrile 2-((1,1-dioxidobenzo[d]isothiazol-3-yl)thio)acetonitrile 80357-08-0 (CAS 80357-08-0)
- Insulin Detemir (CAS 169148-63-4)
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