Celecoxib Impurity 66 CAS CATO-C4X-104366
| CAS No. | CATO-C4X-104366 |
| Molecular Formula | C20H19F3N2O3S |
| Molecular Weight | 424.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 424.44 g/mol gives Celecoxib Impurity 66 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Celecoxib Impurity 66 (CAS CATO-C4X-104366) is a certified pharmaceutical impurity reference standard with the molecular formula C20H19F3N2O3S and a molecular weight of 424.44 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Celecoxib Impurity 66 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 424.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Celecoxib Impurity 66 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H19F3N2O3S |
| Molecular Weight | 424.44 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Celecoxib Standards
- Celecoxib Carboxylic Acid Methyl Ester (CAS 1189893-75-1)
- Celecoxib Impurity 73 (CAS CATO-C4X-104373)
- Celecoxib Impurity 23 (CAS 2247197-65-3)
- Celecoxib Impurity 51 (CAS CATO-C4X-104351)
- Celecoxib Impurity 65 (CAS CATO-C4X-104365)
- Celecoxib Impurity 3(Celecoxib Carboxylic Acid) (CAS 170571-01-4)
- Celecoxib Impurity 18 (CAS 2247197-67-5)
- Celecoxib Impurity 41 (CAS 1803258-57-2)
Recommended Standards
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- (Cys2)-Neuropeptide Y-8-aminooctanoyl-(D-Cys27)-Neuropeptide Y (25-32) (H-3298.0500) (CAS 128806-04-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com