Vardenafil Impurity 48 CAS 224785-72-2
| CAS No. | 224785-72-2 |
| Molecular Formula | C20H26N6O4S |
| Molecular Weight | 446.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Vardenafil Impurity 48 (CAS 224785-72-2, C20H26N6O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Vardenafil Impurity 48 (C20H26N6O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 446.52 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Vardenafil Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H26N6O4S |
| Molecular Weight | 446.52 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2021 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Vardenafil Standards
- Vardenafil Impurity 64 (CAS 224786-03-2)
- Vardenafil Impurity N2 (CAS 448184-54-1)
- Vardenafil Impurity 26 (CAS CATO-C4X-101726)
- Vardenafil Impurity 16 (CAS CATO-C4X-101716)
- Vardenafil Impurity 32 (CAS CATO-C4X-101732)
- Vardenafil USP Related Compound E (CAS 448184-46-1)
- Vardenafil EP impurity A (CAS CATO-C4X-101722)
- Vardenafil EP Impurity A (CAS 2169247-39-4)
Recommended Standards
- tert-Butyl 4-{[(4E)-4-[(2H-1,3-benzodioxol-5-yl)methylidene]-5-oxo-2-sulfanylideneimidazolidin-1-yl]methyl}piperazine-1-carboxylate (CAS 865659-64-9)
- Sildenafil EP Impurity C (CAS 139755-91-2)
- Methyl 6-amino-5-cyano-2-(((3-cyano-6-methylpyridin-2-yl)thio)methyl)-4-(4-ethylphenyl)-4H-pyran-3-carboxylate (CAS 445385-25-1)
- Mizolastine Impurity 9 (CAS CATO-C4X-20069)
- Etoricoxib Impurity 8 (CAS 646459-39-4)
- Calcitonin Impurity 27 (CAS CATO-C4X-221827)
- Rosuvastatin Impurity 139 (CAS CATO-C4X-1169139)
- 4-Methoxyphenethylmagnesium bromide 0.5 M in Tetrahydrofuran (CAS 36278-54-3)
- (4R)-2-Phenylthiazolidine-4-carboxylic acid (CAS 196930-46-8)
- (1H-Pyrrolo[3,2-b]pyridin-5-yl)methanol (CAS 1346569-67-2)
- 2-Benzoyl-3-[(3,4-dichlorobenzenesulfinyl)methyl]-1-benzofuran (CAS 338423-92-0)
- 1-(2,7-Diazaspiro[3.5]nonan-7-yl)ethanone dihydrochloride (CAS 2387598-67-4)
- 2-((3-Cyano-6-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 940814-14-2)
- Influenza PR8 Hemagglutinin Peptide (110-119) (H-6312.0005) (CAS 132031-50-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com