3-Fluoro-4-hydroxy-5-(trifluoromethyl)phenylboronic acid CAS 2260683-55-2

Purity 97%+In StockPharmaceutical Standards
CAS No.2260683-55-2
Molecular FormulaC7H5BF4O3
Molecular Weight223.92 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Fluoro-4-hydroxy-5-(trifluoromethyl)phenylboronic acid CAS 2260683-55-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 223.92 g/mol gives 3-Fluoro-4-hydroxy-5-(trifluoromethyl)phenylboronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 3-Fluoro-4-hydroxy-5-(trifluoromethyl)phenylboronic acid (CAS 2260683-55-2), a certified reference material (molecular formula C7H5BF4O3, MW 223.92 g/mol) for analytical method development and quality control.

3-Fluoro-4-hydroxy-5-(trifluoromethyl)phenylboronic acid (C7H5BF4O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H5BF4O3
Molecular Weight223.92 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1998
Halogen ContentF-containing

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