(2-Fluoro-5-hydroxy-3-(trifluoromethyl)phenyl)boronic acid CAS 2096339-99-8
| CAS No. | 2096339-99-8 |
| Molecular Formula | C7H5BF4O3 |
| Molecular Weight | 223.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2-Fluoro-5-hydroxy-3-(trifluoromethyl)phenyl)boronic acid.
(2-Fluoro-5-hydroxy-3-(trifluoromethyl)phenyl)boronic acid (CAS 2096339-99-8), molecular formula C7H5BF4O3 and molecular weight 223.92 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2-Fluoro-5-hydroxy-3-(trifluoromethyl)phenyl)boronic acid (C7H5BF4O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2-Fluoro-5-hydroxy-3-(trifluoromethyl)phenyl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5BF4O3 |
| Molecular Weight | 223.92 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-Fluoro-6-trifluoromethoxy-phenyl boronic acid (CAS 1261214-72-5)
- 3-Fluoro-4-(trifluoromethoxy)phenylboronic Acid (CAS 187804-79-1)
- (2-Fluoro-3-(trifluoromethoxy)phenyl)boronic acid (CAS 881402-25-1)
- (2-Fluoro-6-hydroxy-4-(trifluoromethyl)phenyl)boronic acid (CAS 2890194-35-9)
- (4-Fluoro-3-(trifluoromethoxy)phenyl)boronic acid (CAS 881402-21-7)
- (5-Fluoro-2-(trifluoromethoxy)phenyl)boronic acid (CAS 866633-26-3)
- 2-Fluoro-5-(trifluoromethoxy)phenylboronic Acid (CAS 881402-22-8)
- 3-Fluoro-4-hydroxy-5-(trifluoromethyl)phenylboronic acid (CAS 2260683-55-2)
Recommended Standards
- (2,3,5,6-Tetrafluoro-4-methoxyphenyl)boronic acid (CAS 871126-20-4)
- (4-(Difluoromethoxy)-3,5-difluorophenyl)boronic acid (CAS 915401-97-7)
- (4-(Difluoromethoxy)-2,5-difluorophenyl)boronic acid (CAS 1628442-69-2)
- 2,2-Dibromomalononitrile (CAS 1885-23-0)
- (2-(Pyridin-3-ylamino)thiazol-4-yl)(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methanone (CAS 1286727-07-8)
- 2-Methyl-5-((1S,2R,3R)-1,2,3,4-tetrahydroxybutyl)furan-3-carboxylic acid (CAS 14048-58-9)
- 2-Amino-N-(4-fluorobenzyl)acetamide (CAS 87429-26-3)
- 3-Amino-1-benzyl-4-(2-chlorophenyl)azetidin-2-one (CAS 1291488-55-5)
- n-[2-chloro-5-(trifluoromethyl)phenyl]-3-oxobutanamide (CAS 585-97-7)
- (1<I>R</I>,8<I>S</I>,9<I>s</I>)-bicyclo[6.1.0]non-4-yn-9-ylmethyl< I>N</I>-succinimide carbonate (CAS 1516551-46-4)
- (R)-Benzyl 3-(ethyl(2-hydroxyethyl)amino)pyrrolidine-1-carboxylate (CAS 1353993-94-8)
- 2-(2-Bromo-5-fluorobenzyl)-4,4-dimethylisoxazolidin-3-one (CAS 81778-83-8)
- 7-Bromo-4,4-dimethyl-3,4-dihydroisoquinolin-1(2H)-one (CAS 1784426-29-4)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com