2-Fluoro-5-(trifluoromethoxy)phenylboronic Acid CAS 881402-22-8
| CAS No. | 881402-22-8 |
| Molecular Formula | C7H5BF4O3 |
| Molecular Weight | 223.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Fluoro-5-(trifluoromethoxy)phenylboronic Acid (CAS 881402-22-8), molecular formula C7H5BF4O3 and molecular weight 223.92 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Fluoro-5-(trifluoromethoxy)phenylboronic Acid (C7H5BF4O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 223.92 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2-Fluoro-5-(trifluoromethoxy)phenylboronic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5BF4O3 |
| Molecular Weight | 223.92 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-Fluoro-6-trifluoromethoxy-phenyl boronic acid (CAS 1261214-72-5)
- 3-Fluoro-4-(trifluoromethoxy)phenylboronic Acid (CAS 187804-79-1)
- (2-Fluoro-3-(trifluoromethoxy)phenyl)boronic acid (CAS 881402-25-1)
- (2-Fluoro-5-hydroxy-3-(trifluoromethyl)phenyl)boronic acid (CAS 2096339-99-8)
- (2-Fluoro-6-hydroxy-4-(trifluoromethyl)phenyl)boronic acid (CAS 2890194-35-9)
- (4-Fluoro-3-(trifluoromethoxy)phenyl)boronic acid (CAS 881402-21-7)
- (5-Fluoro-2-(trifluoromethoxy)phenyl)boronic acid (CAS 866633-26-3)
- 3-Fluoro-4-hydroxy-5-(trifluoromethyl)phenylboronic acid (CAS 2260683-55-2)
Recommended Standards
- Iododifluoroacetyl fluoride (CAS 44507-93-9)
- (4-(Difluoromethoxy)-3,5-difluorophenyl)boronic acid (CAS 915401-97-7)
- (1-(Methoxymethyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl)boronic acid (CAS 1218790-73-8)
- 2-Bromo-2,3,3,3-tetrafluoropropanamide (CAS 422-22-0)
- Fmoc-pentafluoro-D-Phe-OH (CAS 198545-85-6)
- (2R,3R,4S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluorotetrahydrofuran-3-yl benzoate (CAS 121353-90-0)
- 3-(3,5-Bis(trifluoromethyl)phenyl)-1-(2'-(3-(3,5-bis(trifluoromethyl)phenyl)ureido)-[1,1'-binaphthalen]-2-yl)-1-isopropylurea (CAS 2227157-04-0)
- Vinyl heptafluorobutanoate (CAS 356-28-5)
- (2S)-1-(piperidin-4-yl)pyrrolidine-2-carboxylic acid hydrochloride (CAS 1820571-91-2)
- Methyl 5-cyano-3-methylisothiazole-4-carboxylate (CAS 201298-88-6)
- 4-(Difluoromethyl)-6-iodo-3-methoxypicolinic acid (CAS 1807093-34-0)
- 5-Cyclopropoxy-2-iodobenzoic acid (CAS 1243385-39-8)
- 3,4-Dichloro-N-cyclopentylaniline (CAS 557799-54-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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