3-Chloro-2,4-difluorophenol CAS 2268-00-0
| CAS No. | 2268-00-0 |
| Molecular Formula | C6H3ClF2O |
| Molecular Weight | 164.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Chloro-2,4-difluorophenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-Chloro-2,4-difluorophenol (CAS 2268-00-0), molecular formula C6H3ClF2O and molecular weight 164.54 g/mol, is a CATO reference standard with documented purity and traceability.
3-Chloro-2,4-difluorophenol (C6H3ClF2O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3ClF2O |
| Molecular Weight | 164.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-3,4-difluorophenol (CAS 1159512-40-9)
- 2-Chloro-4-(difluoromethyl)pyrimidine (CAS 1261629-31-5)
- 4-Chloro-2,3-difluorophenol (CAS 1261634-63-2)
- 4-Chloro-6-(difluoromethyl)pyrimidine (CAS 1261737-05-6)
- 2-Chloro-5-(difluoromethyl)pyrimidine (CAS 1261869-28-6)
- 4-Chloro-2,6-difluorophenol (CAS 164790-68-5)
- 6-Chloro-2,3-difluorophenol (CAS 186590-18-1)
- 5-Chloro-3,6-difluoropyridin-2-amine (CAS 189281-75-2)
Recommended Standards
- 2-Choro-3,6-difluorophenol (CAS 261762-50-9)
- 3-Chloro-2,6-difluoropyridin-4-amine (CAS 405230-78-6)
- 2-Chloro-4,6-difluorophenol (CAS 2267-99-4)
- 4-Chloro-2,5-difluorophenol (CAS 2268-02-2)
- 3-((2-(2,2,2-Trifluoroacetamido)ethyl)disulfanyl)propanoic acid (CAS 2401831-98-7)
- 8-(3-Phenyl-1,2,4-oxadiazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol (CAS 1239755-06-6)
- 2-(3-Chlorophenyl)-5-phenyl-1,3,4-oxadiazole (CAS 79442-06-1)
- Ethyl 3-benzyl-3-methyloxirane-2-carboxylate (CAS 83769-16-8)
- 4-Chloro-2-picoline (CAS 3678-63-5)
- 2-(Difluoromethyl)-7-methoxy-4H-chromen-4-one (CAS 156909-18-1)
- Methyl 4-aminoquinoline-8-carboxylate (CAS 1416438-65-7)
- Tert-butyl (3aR,6aS)-5-hydroxy-5-methylhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate (CAS 2567756-09-4)
- (S)-2-amino-3-(1-propyl-1h-imidazol-4-yl)propanoic acid (CAS 777076-98-9)
- Semaglutide impurity 227 (CAS CATO-C4X-2226227)
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