Omacycline M+2 impurity CAS 2272886-40-3
| CAS No. | 2272886-40-3 |
| Molecular Formula | C29H42N4O7 |
| Molecular Weight | 558.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 558.67 g/mol gives Omacycline M+2 impurity distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Omacycline M+2 impurity (CAS 2272886-40-3) is a certified pharmaceutical impurity reference standard with the molecular formula C29H42N4O7 and a molecular weight of 558.67 g/mol.
The molecular framework of Omacycline M+2 impurity (C29H42N4O7) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Omacycline M+2 impurity meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H42N4O7 |
| Molecular Weight | 558.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 4 |
Related Omacycline Standards
- Omacycline 4-Beta isomer (CAS 601455-29-2)
- Omacycline 12-amino impurity (CAS 2272886-39-0)
- Omacycline M-2 Impurity (CAS 2272886-35-6)
- Omacycline Impurity 7 (CAS 488819-64-3)
- Omacycline impurity 10 (CAS CATO-C4X-285710)
- Omacycline 7-desmethyl impurity (CAS 2272886-38-9)
- Omacycline Impurity 6 (CAS 1075240-42-4)
- Omacycline 4-one impurity (CAS 885112-31-2)
Recommended Standards
- Lifitegrast Impurity 66 (CAS CATO-C4X-240966)
- Omadacycline Impurity 34 (CAS CATO-C4X-285734)
- Irinotecan Impurity 38 (CAS 143490-54-4)
- Mavacamten Impurity 20 (CAS CATO-C4X-298220)
- Evocalcet Impurity 13 (CAS CATO-C4X-248513)
- Abemaciclib Impurity 176 (CAS CATO-C4X-2937176)
- Paliperidone Impurity 89 (CAS CATO-C4X-172489)
- Methyl 2,4-dibromo-5-(difluoromethoxy)phenylacetate (CAS 1803834-23-2)
- 2-(3-(3-Methoxyphenyl)-1H-pyrazol-1-yl)acetic acid (CAS 957490-48-1)
- Pregabalin Impurity 125 (CAS CATO-C4X-1312125)
- 2-Bromo-3-(difluoromethyl)-5-iodo-6-(trifluoromethyl)pyridine (CAS 1807009-99-9)
- Ulipristal Impurity 21 (CAS CATO-C4X-191521)
- 3-Chloro-2-fluoro-6-propoxypyridine (CAS 1881321-17-0)
- Semaglutide Impurity 190 (CAS CATO-C4X-2226190)
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