Lifitegrast Impurity 66 CAS CATO-C4X-240966
| CAS No. | CATO-C4X-240966 |
| Molecular Formula | C27H30N2O7S2 |
| Molecular Weight | 558.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Lifitegrast Impurity 66 (CAS CATO-C4X-240966, C27H30N2O7S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C27H30N2O7S2, Lifitegrast Impurity 66 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 558.67 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C27H30N2O7S2 |
| Molecular Weight | 558.67 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Lifitegrast Standards
- Lifitegrast Impurity 146 (CAS CATO-C4X-2409146)
- lifitegrast Impurity 21 (CAS CATO-C4X-240921)
- Lifitegrast Impurity 160 (CAS CATO-C4X-2409160)
- Lifitegrast Impurity 103 (CAS CATO-C4X-2409103)
- Lifitegrast Impurity 15 (CAS 2295862-00-7)
- Lifitegrast Impurity 63 (CAS CATO-C4X-240963)
- Lifitegrast Impurity 50 (CAS 2762168-17-0)
- Lifitegrast Impurity 48 (CAS CATO-C4X-240948)
Recommended Standards
- Irinotecan Impurity 38 (CAS 143490-54-4)
- Omacycline M+2 impurity (CAS 2272886-40-3)
- (3E)-1-(4-chlorophenyl)-3-{[(2,4-dichlorophenyl)methoxy]imino}-2-[(1E)-{[(2,4-dichlorophenyl)methoxy]imino}methyl]prop-1-en-1-ol 866136-05-2 8D-044 (CAS 866136-05-2)
- Omadacycline Impurity 34 (CAS CATO-C4X-285734)
- Miconazole Impurity 30 (CAS CATO-C4X-180230)
- Fulvestrant Impurity 29 (CAS CATO-C4X-191729)
- Tedizolid Impurity 26 (CAS CATO-C4X-105426)
- 4-(Benzo[d][1,3]dioxol-5-ylmethylene)-3-phenyloxazolidin-5-one (CAS 6286-57-3)
- 2,5-Dichloro-4-(difluoromethoxy)phenol (CAS 1807178-21-7)
- 5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzo[c][1,2,5]oxadiazole (CAS 2096995-84-3)
- 1-(3-Bromophenyl)butan-2-one (CAS 1184376-39-3)
- (4-Bromo-2-isopropylphenyl)methanamine (CAS 1370601-16-3)
- 2,4-Dibromo-6-fluoropyridin-3-ol (CAS 1421602-80-3)
- Delta-Sleep Inducing Peptide (CAS 62568-57-4)
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