Cefadroxil EP Impurity A(Amoxicillin EP Impurity I) CAS 22818-40-2
| CAS No. | 22818-40-2 |
| Molecular Formula | C8H9NO3 |
| Molecular Weight | 167.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Cefadroxil EP Impurity A(Amoxicillin EP Impurity I) (CAS 22818-40-2), a pharmacopoeial impurity reference standard (molecular formula C8H9NO3, MW 167.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Cefadroxil EP Impurity A(Amoxicillin EP Impurity I) is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 167.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9NO3 |
| Molecular Weight | 167.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
Related Cefadroxil Standards
- Cefadroxil Impurity 17 (CAS 700-63-0)
- Cefadroxil EP Impurity G（Cefradine EP Impurity F/Cefalexin EP Impurity D） (CAS 34876-35-2)
- Cefadroxil Impurity 39 (CAS CATO-C4X-122439)
- Cefadroxil Impurity 27 (CAS 55102-13-1)
- Cefadroxil Impurity 40 (CAS 646536-87-0)
- Cefadroxil Impurity 41 (CAS 68641-64-5)
- Cefadroxil Impurity 36 (CAS CATO-C4X-122436)
- Cefadroxil-d4 (CAS CATO-C4X-122411)
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- Rivaroxaban Impurity 109 HCl (CAS CATO-C4X-1090109)
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- 5-Carbamoyl-3-chloropyridine-2-carboxylic acid (CAS 1200497-79-5)
- Lamotrigine-d3 (CAS 1132746-94-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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