(1-(4-Iodophenyl)-2,5-dimethyl-1h-pyrrole-3-carbonyl)phosphoramidic dichloride CAS 228566-42-5
| CAS No. | 228566-42-5 |
| Molecular Formula | C13H12Cl2IN2O2P |
| Molecular Weight | 457.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(1-(4-Iodophenyl)-2,5-dimethyl-1h-pyrrole-3-carbonyl)phosphoramidic dichloride (CAS 228566-42-5) is a high-purity analytical reference standard with the molecular formula C13H12Cl2IN2O2P and a molecular weight of 457.03 g/mol.
(1-(4-Iodophenyl)-2,5-dimethyl-1h-pyrrole-3-carbonyl)phosphoramidic dichloride (C13H12Cl2IN2O2P) contains a nitrogen-containing heterocyclic scaffold, an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage, chlorine/iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12Cl2IN2O2P |
| Molecular Weight | 457.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2022 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Iodophenyl Standards
- N-(4-Iodophenyl)-1-phenyl-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carbothioamide (CAS 393823-52-4)
- 2-((1-(4-Iodophenyl)-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid (CAS 514182-09-3)
- N-(4-Iodophenyl)-2-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}acetamide (CAS 329778-78-1)
- 1,2-Bis(4-iodophenyl)ethane-1,2-dione (CAS 65699-84-5)
- Ethyl 3-(2-(4-iodophenyl)-5-methyl-7-oxo-1,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)propanoate (CAS 6048-49-3)
- 2-(4-Iodophenyl)-1-phenyl-5-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 919794-88-0)
- N-(4-iodophenyl)-2-((3,4,4-trifluorobut-3-en-1-yl)thio)nicotinamide (CAS 339106-86-4)
- N-(4-iodophenyl)-4-methyl-2-(1-oxoisoindolin-2-yl)pentanamide (CAS 477889-82-0)
Recommended Standards
- 2-((4-Chlorobenzyl)thio)-4-(2-methoxyphenyl)-6-(p-tolyl)nicotinonitrile (CAS 337925-12-9)
- (2-Hydroxy-3,5-diiodophenyl)(piperidin-1-yl)methanone (CAS 1007818-06-5)
- 2-((2-Chlorobenzyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile (CAS 337925-06-1)
- Benzyl 5-bromo-6-iodo-1H-indazole-1-carboxylate (CAS 2416015-78-4)
- 3-spiro[2.2]pentan-2-ylprop-2-ynoic acid (CAS 2138342-82-0)
- 4-(4-Fluorophenyl)-N-[4-(trifluoromethyl)phenyl]piperazine-1-carboxamide (CAS 1024120-50-0)
- 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyrrolidine (CAS 884507-45-3)
- [(3Z)-1-[(4-Methylphenyl)methyl]-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino pentanoate (CAS 303149-55-5)
- Ethyl 2-oxo-4-(pyridin-4-yl)-2,3-dihydrothiazole-5-carboxylate (CAS 886505-28-8)
- 5-Chloro-6-methyl-1H-benzo[d]imidazol-2-amine (CAS 67468-95-5)
- 2,6-Dimethylbenzoylacetonitrile (CAS 677713-07-4)
- 2-(Hydroxymethyl)benzo[d]oxazole-5-acrylic acid (CAS 1803426-66-5)
- n-(2-Ethylphenyl)tetrahydrothiophen-3-amine (CAS 1020958-76-2)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
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