2-((2-Chlorobenzyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile CAS 337925-06-1
| CAS No. | 337925-06-1 |
| Molecular Formula | C27H21ClN2OS |
| Molecular Weight | 456.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-((2-Chlorobenzyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile (CAS 337925-06-1), a certified reference material (molecular formula C27H21ClN2OS, MW 456.99 g/mol) for analytical method development and quality control.
The molecular framework of 2-((2-Chlorobenzyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile (C27H21ClN2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((2-Chlorobenzyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H21ClN2OS |
| Molecular Weight | 456.99 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorobenzyl Standards
- 2-((4-Chlorobenzyl)thio)-4-(2-methoxyphenyl)-6-(p-tolyl)nicotinonitrile (CAS 337925-12-9)
- 4-Chlorobenzyl 4-(3-(5-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)-3-oxopropyl)piperazine-1-carboxylate (CAS 1144035-43-7)
- 3-((4-Chlorobenzyl)thio)-5-((naphthalen-1-yloxy)methyl)-4-phenyl-4H-1,2,4-triazole (CAS 335218-30-9)
- 3-(((4-Chlorobenzyl)thio)methyl)-5-((4-fluorobenzyl)thio)-4-phenyl-4H-1,2,4-triazole (CAS 344270-29-7)
- 5-((2-Chlorobenzyl)thio)-N-(4-methoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321553-39-3)
- 2-((4-Chlorobenzyl)sulfonyl)-1,1-bis(4-chlorophenyl)ethanol (CAS 252026-84-9)
- N-((5-((4-Chlorobenzyl)thio)-4-(4-chlorophenyl)-4H-1,2,4-triazol-3-yl)methyl)-4-methylaniline (CAS 332872-74-9)
- 1-(4-Chlorobenzyl)-3-methyl-4-(3-(trifluoromethyl)benzoyl)-3,4-dihydroquinoxalin-2(1H)-one (CAS 317822-34-7)
Recommended Standards
- (-)-JQ1 (CAS 1268524-71-5)
- (+)-JQ1 (CAS 1268524-70-4)
- (1-(4-Iodophenyl)-2,5-dimethyl-1h-pyrrole-3-carbonyl)phosphoramidic dichloride (CAS 228566-42-5)
- (+/-)-JQ1 (CAS 1268524-69-1)
- 3-Amino-4-cyclobutyl-2-oxobutanamide (CAS 816444-95-8)
- (6-Methylimidazo[1,2-a]pyridin-3-yl)methanamine (CAS 933756-10-6)
- N-(5-(Chloromethyl)thiazol-2-yl)acetamide (CAS 1092696-77-9)
- 2-chloro-N-(4-chloro-2-fluorophenyl)acetamide 380345-39-1 C8H6Cl2FNO HTS007647 (CAS 380345-39-1)
- 4-Iodo-1-propyl-1H-pyrazol-3-amine (CAS 1354706-77-6)
- Fosfomycin Impurity 82 (CAS 789427-15-2)
- N-(Furan-2-ylmethyl)-2-((1-(2-hydroxyethyl)-2-oxo-1,2,5,6,7,8-hexahydroquinazolin-4-yl)thio)acetamide (CAS 941979-15-3)
- Paliperidone Impurity 116 (CAS 1200448-51-6)
- (S)-3-(Benzyloxy)-2-Hydroxypropyl 4-Methylbenzenesulfonate (CAS 16495-04-8)
- Peptide Impurity 82 (CAS 10491-78-8)
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