2-((4-Chlorobenzyl)thio)-4-(2-methoxyphenyl)-6-(p-tolyl)nicotinonitrile CAS 337925-12-9
| CAS No. | 337925-12-9 |
| Molecular Formula | C27H21ClN2OS |
| Molecular Weight | 456.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-((4-Chlorobenzyl)thio)-4-(2-methoxyphenyl)-6-(p-tolyl)nicotinonitrile (CAS 337925-12-9), a certified reference material (molecular formula C27H21ClN2OS, MW 456.99 g/mol) for analytical method development and quality control.
The molecular framework of 2-((4-Chlorobenzyl)thio)-4-(2-methoxyphenyl)-6-(p-tolyl)nicotinonitrile (C27H21ClN2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-((4-Chlorobenzyl)thio)-4-(2-methoxyphenyl)-6-(p-tolyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H21ClN2OS |
| Molecular Weight | 456.99 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorobenzyl Standards
- 2-((2-Chlorobenzyl)thio)-4-(4-methoxyphenyl)-6-(p-tolyl)nicotinonitrile (CAS 337925-06-1)
- 4-Chlorobenzyl 4-(3-(5-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)-3-oxopropyl)piperazine-1-carboxylate (CAS 1144035-43-7)
- 3-((4-Chlorobenzyl)thio)-5-((naphthalen-1-yloxy)methyl)-4-phenyl-4H-1,2,4-triazole (CAS 335218-30-9)
- 3-(((4-Chlorobenzyl)thio)methyl)-5-((4-fluorobenzyl)thio)-4-phenyl-4H-1,2,4-triazole (CAS 344270-29-7)
- 5-((2-Chlorobenzyl)thio)-N-(4-methoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321553-39-3)
- 2-((4-Chlorobenzyl)sulfonyl)-1,1-bis(4-chlorophenyl)ethanol (CAS 252026-84-9)
- N-((5-((4-Chlorobenzyl)thio)-4-(4-chlorophenyl)-4H-1,2,4-triazol-3-yl)methyl)-4-methylaniline (CAS 332872-74-9)
- 1-(4-Chlorobenzyl)-3-methyl-4-(3-(trifluoromethyl)benzoyl)-3,4-dihydroquinoxalin-2(1H)-one (CAS 317822-34-7)
Recommended Standards
- (1-(4-Iodophenyl)-2,5-dimethyl-1h-pyrrole-3-carbonyl)phosphoramidic dichloride (CAS 228566-42-5)
- (-)-JQ1 (CAS 1268524-71-5)
- (2-Hydroxy-3,5-diiodophenyl)(piperidin-1-yl)methanone (CAS 1007818-06-5)
- (+)-JQ1 (CAS 1268524-70-4)
- Ethyl 4-methoxy-3-oxobutanoate, 97% (CAS 66762-68-3)
- 2-(Trifluoromethyl)-5-pyrimidineacetic Acid (CAS 1216002-39-9)
- Benzyl 2-((6-(pyrrolidin-1-yl)pyrimidin-4-yl)thio)acetate (CAS 1171801-55-0)
- (2-Bromophenyl)(3-chloro-5-fluorophenyl)methanol (CAS 1443345-13-8)
- Ethyl 7-(4-(azetidin-1-ylmethyl)phenyl)-7-oxoheptanoate (CAS 898757-28-3)
- 5-(2,3,4,5,6-Pentafluorophenyl)-1H-indole (CAS 893734-39-9)
- Diethyl 3-methylthiophene-2,4-dicarboxylate (CAS 14559-14-9)
- 2,3-Dichloro-4-(ethylsulfonyl)-N-(4-(trifluoromethyl)phenyl)benzamide (CAS 477867-71-3)
- (2E)-4-(4-{[2-chloro-5-(trifluoromethyl)phenyl]sulfonyl}piperazin-1-yl)-4-oxobut-2-enoic acid (CAS 743445-12-7)
- Prolactin-Releasing Peptide (1-31) (human) (CAS 215510-22-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com