Rosuvastatin EP Impurity N CAS 2290571-51-4
| CAS No. | 2290571-51-4 |
| Molecular Formula | C22H26FN3O5S |
| Molecular Weight | 463.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Rosuvastatin EP Impurity N (CAS 2290571-51-4), a pharmacopoeial impurity reference standard (molecular formula C22H26FN3O5S, MW 463.52 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Rosuvastatin EP Impurity N (C22H26FN3O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 463.52 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H26FN3O5S |
| Molecular Weight | 463.52 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rosuvastatin Standards
- Rosuvastatin Impurity 74 (CAS 615263-62-2)
- Rosuvastatin (2S,4S)-Lactone (CAS 1809092-87-2)
- (Z)-Rosuvastatin Lactone (CAS CATO-C4X-1169133)
- Rosuvastatin EP Impurity K (CAS 1422954-12-8)
- Rosuvastatin Impurity 256 (CAS 1422954-13-9)
- Rosuvastatin (2R)-Lactone (CAS CATO-C4X-116941)
- Rosuvastatin EP Impurity D (CAS 503610-43-3)
- Rosuvastatin Impurity 81 (CAS 854898-47-8)
Recommended Standards
- Apremilast-D3 (CAS CATO-C4X-1009129)
- HPI 1 (CAS 599150-20-6)
- 3-((((9h-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-4-yl)propanoic acid (CAS 269078-79-7)
- Rosuvastatin Impurity 82 (CAS 854898-46-7)
- Brivaracetam Impurity 19 (CAS 16496-51-8)
- Baloxavir Impurity 70 (CAS CATO-C4X-210870)
- Deoxycholic acid Impurity 19 (CAS CATO-C4X-335919)
- (S)-1-((R)-piperidine-3-carbonyl)piperidine-3-carboxylic acid dihydrochloride (CAS 448281-69-4)
- Sodium 2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetate (CAS 79427-93-3)
- 4,6-Dibromo-5-chloropyrimidine (CAS 2229563-91-9)
- 4'-Fluoro-[1,1'-biphenyl]-2-amine (CAS 321-63-1)
- 4-Chloro-5,8-dihydro-6H-pyrano[3,4-d]pyrimidin-2-amine (CAS 2171032-51-0)
- 2-Amino-N-(((S)-1-benzylpiperidin-2-yl)methyl)propanamide (CAS 1354032-58-8)
- (Met(O)2?)-Glucagon (1-29) (human, rat, porcine) (CAS 75217-63-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com