Rosuvastatin EP Impurity K CAS 1422954-12-8
| CAS No. | 1422954-12-8 |
| Molecular Formula | C22H26FN3O5S |
| Molecular Weight | 463.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rosuvastatin EP Impurity K (C22H26FN3O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Rosuvastatin EP Impurity K (CAS 1422954-12-8) is a certified pharmaceutical impurity reference standard with the molecular formula C22H26FN3O5S and a molecular weight of 463.52 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Rosuvastatin EP Impurity K under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H26FN3O5S |
| Molecular Weight | 463.52 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rosuvastatin Standards
- Rosuvastatin Impurity 74 (CAS 615263-62-2)
- Rosuvastatin (2S,4S)-Lactone (CAS 1809092-87-2)
- (Z)-Rosuvastatin Lactone (CAS CATO-C4X-1169133)
- Rosuvastatin EP Impurity N (CAS 2290571-51-4)
- Rosuvastatin Impurity 256 (CAS 1422954-13-9)
- Rosuvastatin (2R)-Lactone (CAS CATO-C4X-116941)
- Rosuvastatin EP Impurity D (CAS 503610-43-3)
- Rosuvastatin Impurity 81 (CAS 854898-47-8)
Recommended Standards
- Apremilast-D3 (CAS CATO-C4X-1009129)
- Rosuvastatin Impurity 82 (CAS 854898-46-7)
- HPI 1 (CAS 599150-20-6)
- Venlafaxine Impurity 13 (CAS CATO-C4X-143413)
- Vaborbactam Impurity 3 (CAS CATO-C4X-34773)
- Vildagliptin Impurity 69 (CAS CATO-C4X-110069)
- Tenofovir disoproxil Impurity 127 (CAS CATO-C4X-1076127)
- 2-Hydroxy-4-methoxybenzoyl chloride (CAS 15198-08-0)
- 6-Fluoro-7-methyl-8-nitroquinolin-2(1H)-one (CAS 1420791-36-1)
- 1-(2-Amino-3-methoxyphenyl)ethanone (CAS 42465-54-3)
- L-778123 hydrochloride (CAS 253863-00-2)
- 2-[4-(trifluoromethyl)phenyl]propan-1-ol (CAS 284686-92-6)
- 2-Ethyl-5-hydroxyisoquinolin-2-ium bromide (CAS 4501-30-8)
- Lixisenatide (CAS 320367-13-3（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com