Tedizolid Impurity 71 CAS 2295578-89-9
| CAS No. | 2295578-89-9 |
| Molecular Formula | C14H11BrFNO2 |
| Molecular Weight | 324.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tedizolid Impurity 71 (C14H11BrFNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Tedizolid Impurity 71 (CAS 2295578-89-9, C14H11BrFNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11BrFNO2 |
| Molecular Weight | 324.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Tedizolid Standards
- Tedizolid Impurity 49 (CAS 510729-01-8)
- Tedizolid Impurity 55 (CAS 1643796-25-1)
- Tedizolid Impurity 91 (CAS 1259078-16-4)
- Tedizolid Impurity 13 (CAS 2095840-91-6)
- Tedizolid Impurity 90 (CAS CATO-C4X-105490)
- Tedizolid Impurity 44 (CAS 92159-87-0)
- Tedizolid impurity 95 (CAS CATO-C4X-105495)
- Tedizolid Impurity 18 (CAS 2044709-71-7)
Recommended Standards
- 2-(2,5-Dichlorobenzamido)-5-methylbenzoic acid (CAS 1036516-96-7)
- N-(4-Bromo-2-fluorophenyl)-4-methoxybenzamide (CAS 438481-18-6)
- 1-iodo-4-(2-phenylethoxy)benzene (CAS 1044065-94-2)
- N-(4-Bromo-2-fluorophenyl)-2-methoxybenzamide (CAS 420092-67-7)
- Chlorprothixene EP Impurity A (CAS 4295-65-2)
- Betamethasone Impurity 125 (CAS CATO-C4X-1437125)
- Sunitinib Impurity 7 (CAS CATO-C4X-13337)
- 4-(2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol (CAS 805239-56-9)
- N-Nitroso-N-cyclohexylaniline (CAS 54955-24-7)
- Ethyl 2-phenyloxazole-5-carboxylate (CAS 39819-40-4)
- 3-Amino-N-(4-methoxyphenyl)propanamide (CAS 770652-56-7)
- 5-(2,4-Difluorophenoxymethyl)thiophene-2-carboxylic acid (CAS 934127-23-8)
- 5-Hexanoyl-2,2-dimethylcyclopentan-1-one (CAS 1540837-58-8)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
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